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MOUSE Anti-HUMAN C6 Antibody

MOUSE Anti-HUMAN C6 Antibody size: 100ug 597

Supplier MBS MONO
Price 597
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asC6
Other names Complement component C6, N/A, complement component 6, complement component C6, complement component C6
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameC6
Gene name synonimsN/A
Other gene names C6, N/A, N/A, C6
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone056B-214, 2, 2, 4
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC), Deficiency of C6 results in susceptibility to bacterial infection, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, This enables the formation of the C5b-7 precursor complex, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_This item recognises MAC, a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum, anchoring the molecule to the membrane, they also binds complement component 7, C6 This item recognises complement component 6 (C6)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: ELISA (EIA), Flow Cytometry (FACS), Immunohistology - Frozen (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetC6
Short nameMOUSE Anti-HUMAN C6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens complement component 6 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Alternative to gene target C6 and IDBG-127938 and ENSMUSG00000022181 and 12274, C6 and IDBG-18604 and ENSG00000039537 and 729, C6 and IDBG-629747 and ENSBTAG00000014177 and 507749, Extracellular, classical pathway and biological process this GO :0019835 and cytolysis and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process, protein binding, this GO :0001701 and in utero embryonic development and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0005515: protein binding, this GO :0005515: protein binding, complement component 6
Identity 1339
Gene C6
Long gene name complement C6
Synonyms gene name complement component 6
Locus 5p13, 1
Discovery year 2001-06-22
GenBank acession J05024
Entrez gene record 729
Classification Sushi domain containing Complement system
Havana BLAST/BLAT OTTHUMG00000094781
Locus Specific Databases C6base: Mutation registry for C6 deficiency LRG_29

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