Name : MOUSE Anti-HUMAN C7 Antibody
Supplier : MBS MONO
Price :597
SKU : GEN7069812345
| Also known as | C7 |
| Other names | Complement component C7, N/A, complement component 7, complement component C7, complement component C7 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | C7 |
| Gene name synonims | N/A |
| Other gene names | C7, N/A, N/A, C7 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 030-113, 4, 5, 7 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | , C7 deficiency is associated with increased susceptibility to recurrent infections, Removal of Sodium Azide is recommended prior to use in functional assays, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The factor I domain of C7 binds the C terminus of the C5 alpha-chain, This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Note that This item does not recognise membrane bound complement membrane attack complex, _x000D__x000D_This item inhibits lysis of sensitised sheep erythrocytes, a 110 kDa glycoprotein present in the blood serum, acting as a membrane anchor, in particular by <, /i>, C7 This item recognises complement component 7 (C7), Neisseria meningitides<, i> |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 0 mg/ml, IgG concentration 1 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Functional Assay (FA), Western Blot (WB), ELISA (EIA) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | C7 |
| Short name | MOUSE Anti-HUMAN C7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens complement component 7 (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Alternative to gene target | BT, C7 and IDBG-18519 and ENSG00000112936 and 730, C7 and IDBG-259737 and ENSMUSG00000079105 and 109828, Extracellular, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0019835 and cytolysis and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0006883 and cellular sodium ion homeostasis and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0005515: protein binding, this GO :0005515: protein binding, 69954 and IDBG-629869 and ENSBTAG00000011766 and 507339, complement component 7 |
| Identity | 1346 |
| Gene | C7 |
| Long gene name | complement C7 |
| Synonyms gene name | complement component 7 |
| Locus | 5p13, 1 |
| Discovery year | 2001-06-22 |
| GenBank acession | J03507 |
| Entrez gene record | 730 |
| Classification | Sushi domain containing Complement system |
| Havana BLAST/BLAT | OTTHUMG00000150340 |
| Locus Specific Databases | C7base: Mutation registry for C7 deficiency LRG_30 |