Name : MOUSE Anti-HUMAN C8 Antibody
Supplier : MBS MONO
Price :597
SKU : GEN9843356323
| Also known as | C8 |
| Other names | Complement component 8 subunit beta, Complement component C8 beta chain, beta polypeptide, complement component 8, complement component 8 subunit beta, complement component C8 beta chain, complement component C8 beta chain preproprotein |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | C8 |
| Gene name synonims | N/A |
| Other gene names | C8B, N/A, N/A, C8B |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 056B-373 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC), C8 binds to the C5b-7 complex, C8 deficiencies can cause recurring bacterial infections, C8 is a terminal component of the complement system, C8 is thought to contain lipid binding sites, Furthermore, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Defects in the alpha chain of C8 can result in complement C8 deficiency type I, a 151 kDa member of the complement C6/C7/C8/C9 family, anchored to the membrane, and important to MAC assembly, creating C5b-8, facilitating the insertion of MAC into the membrane, in particular from <, part of both the complement membrane attack complex (MAC), present in blood serum, /i>, C8 This item recognises complement component 8 (C8), Neisseria meningitides<, i> |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 0mg/ml, IgG concentration 1 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Western Blot (WB), ELISA (EIA) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | C8 |
| Short name | MOUSE Anti-HUMAN C8 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens C8 (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Identity | 5079 |
| Gene | HOX3A |
| Long gene name | homeobox C8 |
| Synonyms gene | HOX3 |
| Synonyms gene name | homeo box C8 |
| Synonyms | HOXC8 |
| Locus | 12q13, 13 |
| Discovery year | 1990-06-15 |
| GenBank acession | X99680 |
| Entrez gene record | 3224 |
| Pubmed identfication | 1973146 1358459 |
| Classification | HOXL subclass homeoboxes |
| Havana BLAST/BLAT | OTTHUMG00000160032 |