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MOUSE Anti-HUMAN CD140a Antibody

MOUSE Anti-HUMAN CD140a Antibody size: 100ug 569

Supplier MBS MONO
Price 569
Size 100ug
Also known asCD140a
Other names Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140 antigen-like family member A, CD140a antigen, CD140a antigen, PDGF-R-alpha, PDGFR-alpha, PDGFRA/BCR fusion, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, Platelet-derived growth factor receptor alpha, alpha polypeptide, alpha-type platelet-derived growth factor receptor, platelet-derived growth factor receptor, platelet-derived growth factor receptor 2, platelet-derived growth factor receptor alpha, rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein, platelet-derived growth factor receptor alpha
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD140a
Gene name synonimsN/A
Other gene names CD140A, PDGF-R-alpha, PDGFR-2, PDGFR-2, PDGFR-alpha, PDGFR2, PDGFR2, PDGFRA, RHEPDGFRA, RHEPDGFRA, PDGFRA
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone35248 (57/20)
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity , Both PDGF receptor alpha and beta are members of the class III subfamily of receptor tyrosine kinases, PDGF R beta binds PDGF-BB and AB but not PDGF-AA, PDGF is a major serum mitogen that can exist as a homo- or heterodimeric protein consisting of disulphide-linked PDGF-A and PDGF-B chains, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cellsurface PDGF receptors with different affinities, Removal of Sodium Azide is recommended prior to use in functional assays, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ND50 was determined as 0, The PDGF-AA, This clone has been reported for use in functional studies, This particular antibody might cross react with speacies outside of the listed ones, Whereas PDGF receptor alpha binds all three isoforms with high affinity, 2-0, 6 ug/ml for blocking 10 ng/ml of PDGF-AA biological activity on a quiescent confluent cell culture of human WS1 cells, CD140a This item is specific for PDGF receptor alpha
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, 1
Storage and shipping Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: ELISA (EIA), Western Blot (WB), Immunohistology - Paraffin (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD140a
Short nameMOUSE Anti-HUMAN CD140a Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD140a (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 8803
Gene PDGFRA
Long gene name platelet derived growth factor receptor alpha
Synonyms gene name alpha polypeptide , platelet-derived growth factor receptor
Synonyms CD140a PDGFR2 GAS9
Locus 4q12
Discovery year 1989-05-19
GenBank acession D50001
Entrez gene record 5156
Pubmed identfication 8643452
RefSeq identity NM_006206
Classification I-set domain containing CD molecules Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000128699
Locus Specific Databases LRG_309

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