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MOUSE Anti-HUMAN CD169:FITC Antibody

MOUSE Anti-HUMAN CD169:FITC Antibody size: 100ug 448

Supplier MBS MONO
Price 448
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD169
Other names Sialic acid-binding Ig-like lectin 1, Sialoadhesin, sialic acid binding Ig-like lectin 1, sialic acid-binding Ig-like lectin 1, sialic acid-binding immunoglobulin-like lectin 1, sialoadhesin, sialoadhesin, sialoadhesin
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD169
Gene name synonimsN/A
Other gene names CD169, SIGLEC-1, SIGLEC1, SN, SN, Siglec-1, dJ1009E24, 1, SIGLEC1
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone7-239
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD169 is highly expressed by dendritic cells and on stromal macrophages in the spleen, NK cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD169 is a macrophage-restricted interaction molecule which binds to sialylated ligands on haematopoietic cells, _x000D__x000D_Clone 7-239 completely inhibits erythrocyte rosetting around Sn+ transductants, a subset of CD8+ T cells and B cells, a type I transmembrane glycoprotein and prototypic member of the Siglec (sialic acid binding Ig-like lectin) family, and studies have shown high expression of CD169 on macrophages in the inflammatory conditions rheumatoid arthritis and atherosclerosis, bone marrow and lymph nodes and to a lesser extent in liver, designated Siglec-1, including neutrophils, lungs and gut, monocytes, otherwise known as Sialoadhesin (Sn), through recognition of sialic acid in the alpha-2, 3- glycosidic linkage, CD169 This item specifically recognises human CD169
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD169:
Short nameMOUSE Anti-HUMAN CD169:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name sapiens CD169:fluorecein (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11127
Gene SIGLEC1
Long gene name sialic acid binding Ig like lectin 1
Synonyms gene SN
Synonyms gene name sialoadhesin , sialoadhesin sialic acid binding Ig-like lectin 1
Synonyms SIGLEC-1 CD169 FLJ00051 FLJ00055 FLJ00073 FLJ32150 dJ1009E24, 1 sialoadhesin
Locus 20p13
Discovery year 1995-03-15
GenBank acession AF230073
Entrez gene record 6614
Pubmed identfication 8530048
RefSeq identity NM_023068
Classification C2-set domain containing I-set domain containing CD molecules Sialic acid binding Ig like lectins V-set domain containing
Havana BLAST/BLAT OTTHUMG00000031757

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