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MOUSE Anti-HUMAN CD178 Antibody

MOUSE Anti-HUMAN CD178 Antibody size: 200ug 713

Supplier MBS MONO
Price 713
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD178
Other names APTL, Apoptosis antigen ligand, CD95 ligand, CD95 ligand, CD95-L, CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, FasL, Soluble Fas ligand, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor ligand superfamily member 6, apoptosis (APO-1) antigen ligand 1, apoptosis antigen ligand, fas antigen ligand, member 6, member 6), membrane form, sFasL, soluble formAlternative name(s):Receptor-binding FasL ectodomain, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 6, tumor necrosis factor ligand superfamily member 6
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD178
Gene name synonimsN/A
Other gene names ALPS1B, APL, APT1LG1, APT1LG1, APTL, APTL, CD178, CD95-L, CD95-L, CD95L, CD95L, FASL, FASL, FASLG, Fas ligand, FasL, FasL ICD, SPA, TNFSF6, TNFSF6, sFasL, FASLG
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone10F2
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Binding of CD178 to Fas (CD95) results in the induction of apoptosis, CD178 is a member of the TNF family, CD178 plays an important role in T cell development and cytotoxicity, Clone 10F2 is reported to block the activity of Fas ligand, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The protein may exist as either a membrane bound or a cleaved soluble form, This particular antibody might cross react with speacies outside of the listed ones, a 40kDa glycoprotein also known as Fas ligand (CD95L), which is expressed by activated T lymphocytes and NK cells, CD178 This item recognises the human CD178 cell surface antigen
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: ELISA (EIA), Flow Cytometry (FACS), Immunoprecipitation (IP)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD178
Short nameMOUSE Anti-HUMAN CD178 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD178 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11936
Gene FASLG
Long gene name Fas ligand
Synonyms gene APT1LG1 TNFSF6
Synonyms gene name member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily
Synonyms FasL CD178
Locus 1q24, 3
Discovery year 1994-12-09
GenBank acession U11821
Entrez gene record 356
Pubmed identfication 7826947 9022072
Classification Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000034841
Locus Specific Databases FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58

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