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MOUSE Anti-HUMAN CD221 Antibody

MOUSE Anti-HUMAN CD221 Antibody size: 200ug 503

Supplier MBS MONO
Price 503
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD221
Other names IGF-I receptor, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, insulin-like growth factor 1 receptor, insulin-like growth factor 1 receptor, insulin-like growth factor I receptor, soluble IGF1R variant 1, soluble IGF1R variant 2, insulin-like growth factor 1 receptor
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD221
Gene name synonimsN/A
Other gene names CD221, IGF-I receptor, IGF1R, IGFIR, IGFR, JTK13, IGF1R
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone1H7
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits, Clone 1H7 is reported to partically block binding of IGF-I and IGF-II to CD221, Clone 1H7 recognises an epitope in the alpha subunits of CD221, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ligands for CD221 include IGF-I and IGF-II, This particular antibody might cross react with speacies outside of the listed ones, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor), brain, demonstrated by Western blotting CD221 is expressed in a range of tissues, including kidney, liver, mammary gland, ovary and skin, placenta, resulting in phosphorylation of several intracellular signalling proteins, which bind to CD221 and activate tyrosine kinase activity, CD221 This item recognises human CD221
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunohistology - Paraffin (IHC), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD221
Short nameMOUSE Anti-HUMAN CD221 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD221 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 5465
Gene IGF1R
Long gene name insulin like growth factor 1 receptor
Synonyms gene name insulin-like growth factor 1 receptor
Synonyms JTK13 CD221 IGFIR MGC18216 IGFR
Locus 15q26, 3
Discovery year 1988-07-07
GenBank acession M69229
Entrez gene record 3480
Pubmed identfication 1316909
RefSeq identity NM_000875
Classification CD molecules Fibronectin type III domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000149851
Locus Specific Databases LOVD - Leiden Open Variation Database LRG_1055

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