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MOUSE Anti-HUMAN CD227:FITC Antibody

MOUSE Anti-HUMAN CD227:FITC Antibody size: 100ug 492

Supplier MBS MONO
Price 492
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD227
Other names Breast carcinoma-associated antigen DF3, CA 15-3, CD_antigen: CD227Cleaved into the following 2 chains:Mucin-1 subunit alpha, Cancer antigen 15-3, Carcinoma-associated mucin, DF3 antigen, EMA, Episialin, H23 antigen, H23AG, KL-6, Krebs von den Lungen-6, MUC1-NT, MUC1-alpha, MUC1-betaAlternative name(s):MUC1-CT, Mucin-1, Mucin-1 subunit beta, PEM, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, breast carcinoma-associated antigen DF3, cancer antigen 15-3, carcinoma-associated mucin, cell surface associated, episialin, krebs von den Lungen-6, mucin 1, mucin 1, mucin-1, peanut-reactive urinary mucin, polymorphic epithelial mucin, transmembrane, tumor associated epithelial mucin, tumor-associated epithelial membrane antigen, tumor-associated mucin, mucin-1 isoform 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD227
Gene name synonimsN/A
Other gene names CA 15-3, CA 15-3, CD227, EMA, EMA, H23AG, KL-6, KL-6, MAM6, MUC-1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1, MUC1-NT, MUC1-alpha, MUC1-beta, MUC1/ZD, PEM, PEM, PEMT, PUM, PUM, PUM, MUC1
ClonalityMonoclonal
Immunoglobulin isotypeIgG3
CloneC595 (NCRC48)
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD227 is expressed on most secretory epithelium, Clone C595 recognises the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This item recognises CD227, This particular antibody might cross react with speacies outside of the listed ones, This protein is overexpressed abundantly in >, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates, including mammary gland and some hematopoietic cells, 90% breast carcinomas and metastases, CD227 Mucins are a family of high molecular weight
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunofluorescence (IF), Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD227:
Short nameMOUSE Anti-HUMAN CD227:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name sapiens CD227:fluorecein (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 7508
Gene MUC1
Long gene name cell surface associated , mucin 1
Synonyms gene PUM MCKD1
Synonyms gene name mucin 1, transmembrane medullary cystic kidney disease 1 (autosomal dominant)
Synonyms CD227 PEM ADMCKD ADMCKD1 MCKD MCD
Locus 1q22
Discovery year 1986-01-01
GenBank acession J05581
Entrez gene record 4582
Pubmed identfication 1697589 23396133
RefSeq identity NM_002456
Classification Mucins CD molecules
Havana BLAST/BLAT OTTHUMG00000035681

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