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MOUSE Anti-HUMAN CD253:Low Endotoxin Antibody

MOUSE Anti-HUMAN CD253:Low Endotoxin Antibody size: 500ug 685

Supplier MBS MONO
Price 685
Size 500ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD253
Other names Apo-2 ligand, Apo-2 ligand, Apo-2L, TNF-related apoptosis inducing ligand TRAIL, TNF-related apoptosis-inducing ligand, Tumor necrosis factor ligand superfamily member 10, chemokine tumor necrosis factor ligand superfamily member 10, member 10, member 10, tumor necrosis factor (ligand) family, tumor necrosis factor (ligand) superfamily, tumor necrosis factor apoptosis-inducing ligand splice variant delta, tumor necrosis factor ligand superfamily member 10, tumor necrosis factor ligand superfamily member 10 isoform 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD253
Gene name synonimsN/A
Other gene names APO2L, APO2L, Apo-2L, Apo-2L, CD253, TL2, TNFSF10, TRAIL, TRAIL, TNFSF10
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone200000
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity DcR1 and DcR2, Most normal tissues are resistant to TRAIL induced apoptosis due to their expression of decoy receptors, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TRAIL induces apoptosis via the receptors DR4 and DR5, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_TRAIL is a cytotoxic protein closely related to Fas (CD95), _x000D__x000D_This antibody neutralises TRAIL activity, activated lymphocytes and on syncytiotrophoblast cells in first trimester pregnancy, also known as CD253, which antagonise TRAIL activity, which induces extensive apoptosis in a range of cell types, CD253 This item recognises the 281 amino acid protein termed TNF related apoptosis-inducing ligand (TRAIL), _x000D_TRAIL is expressed by cell lines
Purification methodN/A
Form/AppearanceLow Endotoxin (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, the antibody should be stored at -20 degrees Celsius
Tested applications: Functional Assay (FA), Western Blot (WB), Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD253: Endotoxin
Short nameMOUSE Anti-HUMAN CD253:Low Endotoxin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD253:Low Endotoxin (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11925
Gene TNFSF10
Long gene name tumor necrosis factor superfamily member 10
Synonyms gene name member 10 , tumor necrosis factor (ligand) superfamily
Synonyms TRAIL Apo-2L TL2 CD253
Locus 3q26
Discovery year 1998-12-04
GenBank acession U37518
Pubmed identfication 8777713 8663110
Classification Tumor necrosis factor superfamily CD molecules
Havana BLAST/BLAT OTTHUMG00000156917

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