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MOUSE Anti-HUMAN CD261 Antibody

MOUSE Anti-HUMAN CD261 Antibody size: 200ug 464

Supplier MBS MONO
Price 464
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD261
Other names Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A, cytotoxic TRAIL receptor, death receptor 4, member 10a, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 10A, tumor necrosis factor receptor superfamily member 10a variant 2, tumor necrosis factor receptor superfamily member 10A
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD261
Gene name synonimsN/A
Other gene names APO2, APO2, CD261, DR4, DR4, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, TRAILR-1, TRAILR1, TRAILR1, TNFRSF10A
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneDR-4-02
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity DR4 is a type I transmembrane protein of 468 amino acids, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The binding of TRAIL to DR4 triggers the activation of pro-caspases 8 and 10, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_DR4 plays a role in inducing cell death, also known as CD261 or TRAIL- R1, leading to apoptosis, peripheral blood leucocytes, thymus and in a variety of tumour-derived cell lines, which is expressed in most human tissues including spleen, CD261 This item is specific for human death receptor 4 (DR4)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunoprecipitation (IP)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD261
Short nameMOUSE Anti-HUMAN CD261 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD261 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11904
Gene TNFRSF10A
Long gene name TNF receptor superfamily member 10a
Synonyms gene name member 10a , tumor necrosis factor receptor superfamily
Synonyms DR4 Apo2 TRAILR-1 CD261
Locus 8p21, 3
Discovery year 1998-12-04
GenBank acession U90875
Entrez gene record 8797
Pubmed identfication 9311998 9082980
RefSeq identity NM_003844
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000097843

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