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MOUSE Anti-HUMAN CD263:FITC Antibody

MOUSE Anti-HUMAN CD263:FITC Antibody size: 100ug 464

Supplier MBS MONO
Price 464
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD263
Other names Antagonist decoy receptor for TRAIL/Apo-2L, DcR1, Decoy TRAIL receptor without death domain, Decoy receptor 1, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TNF-related apoptosis-inducing ligand receptor 3, TRAIL receptor 3, TRAIL receptor without an intracellular domain, TRAIL-R3, Tumor necrosis factor receptor superfamily member 10C, antagonist decoy receptor for TRAIL/Apo-2L, cytotoxic TRAIL receptor-3, decoy TRAIL receptor without death domain, decoy receptor 1, decoy without an intracellular domain, lymphocyte inhibitor of TRAIL, member 10c, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 10C, tumor necrosis factor receptor superfamily member 10C
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD263
Gene name synonimsN/A
Other gene names CD263, DCR1, DCR1, DCR1-TNFR, DcR1, LIT, LIT, TNFRSF10C, TRAIL receptor 3, TRAIL-R3, TRAIL-R3, TRAILR3, TRAILR3, TRID, TRID, TNFRSF10C
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone2B8
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, CD263 is a member of the tumour necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL), CD263 is expressed in normal tissues including heart, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_The 2B8 antibody does not inhibit DcR1 (CD263) inhibitory function in TRAIL-induced apoptosis, a 60 Kd cell surface protein, but instead plays an important role in inhibiting TRAIL-induced apoptosis, but weakly expressed in tumour cells, skeletal tissues and peripheral blood neutrophils, which is otherwise known as decoy receptor 1 (DcR1), CD263 This item recognises human CD263
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD263:
Short nameMOUSE Anti-HUMAN CD263:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name sapiens CD263:fluorecein (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11906
Gene TNFRSF10C
Long gene name TNF receptor superfamily member 10c
Synonyms gene name decoy without an intracellular domain , member 10c, tumor necrosis factor receptor superfamily
Synonyms DcR1 TRAILR3 LIT TRID CD263
Locus 8p21, 3
Discovery year 1998-12-04
GenBank acession AF012536
Entrez gene record 8794
Pubmed identfication 9314565 9325248
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000097844

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