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MOUSE Anti-HUMAN CD266:FITC Antibody

MOUSE Anti-HUMAN CD266:FITC Antibody size: 0.025 miligrams 243

Supplier MBS MONO
Price 243
Size 0.025 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD266
Other names FGF-inducible 14, FGF-inducible 14, Fibroblast growth factor-inducible immediate-early response protein 14, Tumor necrosis factor receptor superfamily member 12A, Tweak-receptor, fibroblast growth factor-inducible immediate-early response protein 14, member 12A, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 12A, tweak-receptor, type I transmembrane protein Fn14, tumor necrosis factor receptor superfamily member 12A
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD266
Gene name synonimsN/A
Other gene names CD266, FGF-inducible 14, FN14, FN14, TNFRSF12A, TWEAKR, TweakR, TNFRSF12A
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
CloneITEM-4
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The interaction between CD266 and its ligand CD255 (TWEAK), This particular antibody might cross react with speacies outside of the listed ones, a 14kDa type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, and also with Rat-1 cells in flow cytometry, and at elevated levels by human brain and liver tumours, and studies have shown that CD255-induced apoptosis of some tumour cell lines is mediated by CD266 Clone ITEM-4 is cross-reactive with mouse CD266, including the heart, induces the proliferation and migration of endothelial cells and also angiogenesis, lung and kidney, otherwise known as Fn14/TWEAK Receptor, CD266 This item recognises human CD266
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD266:
Short nameMOUSE Anti-HUMAN CD266:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name sapiens CD266:fluorecein (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 18152
Gene TNFRSF12A
Long gene name TNF receptor superfamily member 12A
Synonyms gene name member 12A , tumor necrosis factor receptor superfamily
Synonyms FN14 TweakR CD266
Locus 16p13, 3
Discovery year 2002-12-20
GenBank acession AB035480
Pubmed identfication 10751351 10551889
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000129001

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