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MOUSE Anti-HUMAN CD275 Antibody

MOUSE Anti-HUMAN CD275 Antibody size: 200ug 531

Supplier MBS MONO
Price 531
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD275
Other names B7 homolog 2, B7 homolog 2, B7 homologue 2, B7-H2, B7-like protein Gl50, B7-like protein Gl50, B7-related protein 1, B7-related protein 1, ICOS ligand, ICOS ligand, inducible T-cell co-stimulator ligand, transmembrane protein B7-H2 ICOS ligand, ICOS ligand
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD275
Gene name synonimsN/A
Other gene names B7-H2, B7-H2, B7H2, B7H2, B7RP-1, B7RP-1, B7RP1, B7RP1, CD275, GL50, ICOS-L, ICOSL, ICOSL, ICOSLG, KIAA0653, LICOS, ICOSLG
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneMIH11
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD275 has an important physiological role in the reactivation of effector/memory T cells on the endothelium, CD275 is a member of the B7 family, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD275 is expressed on activated B-cells, _x000D__x000D_MIH11 is reported to partially block the interaction between CD275 and CD278, _x000D__x000D_The CD278-CD275 pathway is thought to be critical in the immune response to transplants, allergies and autoimmune diseases, also known as ICOS ligand (inducible T cell co-stimulator ligand), and interaction with its receptor CD278 (ICOS) plays an important role in T cell co-stimulation and inflammatory immune reactions, epithelial cells and muscle cells, monocytes and dendritic cells and is also induced on non-lymphoid tissue cells such as endothelial cells, thus controlling entry of immune cells into inflamed tissue, CD275 This item detects CD275
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunohistology - Frozen (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD275
Short nameMOUSE Anti-HUMAN CD275 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD275 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 17087
Gene ICOSLG
Long gene name inducible T-cell costimulator ligand
Synonyms gene ICOSL
Synonyms KIAA0653 GL50 B7-H2 B7RP-1 B7H2 B7RP1 ICOS-L CD275
Synonyms name B7-related protein 1 B7 homologue 2 B7 homolog 2
Locus 21q22, 3
Discovery year 2003-12-12
GenBank acession AB014553
Entrez gene record 23308
Pubmed identfication 9734811 11007762
RefSeq identity NM_015259
Classification Endogenous ligands C2-set domain containing CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000086920

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