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MOUSE Anti-HUMAN CD283 Antibody

MOUSE Anti-HUMAN CD283 Antibody size: 200ug 879

Supplier MBS MONO
Price 879
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD283
Other names N/A, Toll-like receptor 3, toll-like receptor 3, toll-like receptor 3, toll-like receptor 3
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD283
Gene name synonimsN/A
Other gene names CD283, IIAE2, N/A, TLR3, TLR3
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone7, TLR3
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity , Cell surface expression of TLR3 has been reported on MRC-5 fibroblasts This antibody has been shown to suppress poly (I) : poly C mediated IFN beta production by these cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TLR3 is a member of the Toll-like receptor (TLR) family and functions as a receptor for double-stranded (ds) RNA, TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, This particular antibody might cross react with speacies outside of the listed ones, otherwise known as CD283, CD283 This item recognises human and canine TLR3, They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration5 mg/ml, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunoprecipitation (IP), Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD283
Short nameMOUSE Anti-HUMAN CD283 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD283 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11849
Gene TLR3
Long gene name toll like receptor 3
Synonyms gene name toll-like receptor 3
Synonyms CD283
Locus 4q35, 1
Discovery year 1998-06-25
GenBank acession U88879
Entrez gene record 7098
Pubmed identfication 9435236
Classification CD molecules Toll like receptors
Havana BLAST/BLAT OTTHUMG00000160345
Locus Specific Databases TLR3base: Mutation registry for Influenza-associated encephalopathy LRG_117

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