MOUSE Anti-HUMAN CD284:Biotin Antibody

MOUSE Anti-HUMAN CD284:Biotin Antibody size: 100ug 486

Price 486

Size 100ug

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Also known as	CD284
Other names	Toll-like receptor 4, hToll, hToll, homolog of Drosophila toll, toll-like receptor 4, toll-like receptor 4, toll-like receptor 4 isoform C
Category	Antibodies
Subcategory	Mnoclonal antibodies
Gene name	CD284
Gene name synonims	N/A
Other gene names	ARMD10, CD284, N/A, TLR-4, TLR4, TOLL, TLR4
Clonality	Monoclonal
Immunoglobulin isotype	IgG2a
Clone	HTA125
Host organism	Mouse (Mus musculus)
Species reactivity	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity	Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TLR4, TLR4 is weakly expressed by resting cells, TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule, This antibody has been demonstrated to block activation of monocytes with LPS, This particular antibody might cross react with speacies outside of the listed ones, also known as CD284, but is upregulated following stimulation with LPS, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages, CD284 This item recognises the human Toll like receptor 4 (TLR4) cell surface antigen
Purification method	N/A
Form/Appearance	Biotin (Purified IgG conjugated to Biotin - liquid)
Concentration	1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping	Avoid repeated freezing and thawing as this may denature the protein, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:	Flow Cytometry (FACS)
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Conjugation	Biotinylated
Gene target	CD284:
Short name	MOUSE Anti-HUMAN CD284: Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Label	Biotin
Alternative name	sapiens CD284:biotinilated (Antibody to), MOUSE antibody to-H
Alternative technique	antibodies
Identity	11850
Gene	TLR4
Long gene name	toll like receptor 4
Synonyms gene name	toll-like receptor 4
Synonyms	hToll CD284 TLR-4 ARMD10
Locus	9q33, 1
Discovery year	1998-06-25
GenBank acession	U88880
Entrez gene record	7099
Pubmed identfication	9435236 9237759
RefSeq identity	NM_138554
Classification	CD molecules Toll like receptors
Havana BLAST/BLAT	OTTHUMG00000021046

MOUSE Anti-HUMAN CD284:Biotin Antibody

MOUSE Anti-HUMAN CD284:Biotin Antibody size: 100ug 486

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