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MOUSE Anti-HUMAN CD284:FITC Antibody

MOUSE Anti-HUMAN CD284:FITC Antibody size: 100ug 486

Supplier MBS MONO
Price 486
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD284
Other names Toll-like receptor 4, hToll, hToll, homolog of Drosophila toll, toll-like receptor 4, toll-like receptor 4, toll-like receptor 4 isoform C
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD284
Gene name synonimsN/A
Other gene names ARMD10, CD284, N/A, TLR-4, TLR4, TOLL, TLR4
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneHTA125
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TLR4, TLR4 is weakly expressed by resting cells, TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule, This antibody has been demonstrated to block activation of monocytes with LPS, This particular antibody might cross react with speacies outside of the listed ones, also known as CD284, but is upregulated following stimulation with LPS, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages, CD284 This item recognises the human Toll like receptor 4 (TLR4) cell surface antigen
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD284:
Short nameMOUSE Anti-HUMAN CD284:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name sapiens CD284:fluorecein (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11850
Gene TLR4
Long gene name toll like receptor 4
Synonyms gene name toll-like receptor 4
Synonyms hToll CD284 TLR-4 ARMD10
Locus 9q33, 1
Discovery year 1998-06-25
GenBank acession U88880
Entrez gene record 7099
Pubmed identfication 9435236 9237759
RefSeq identity NM_138554
Classification CD molecules Toll like receptors
Havana BLAST/BLAT OTTHUMG00000021046

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