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MOUSE Anti-HUMAN CD284:Low Endotoxin Antibody

MOUSE Anti-HUMAN CD284:Low Endotoxin Antibody size: 500ug 647

Supplier MBS MONO
Price 647
Size 500ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD284
Other names Toll-like receptor 4, hToll, hToll, homolog of Drosophila toll, toll-like receptor 4, toll-like receptor 4, toll-like receptor 4 isoform C
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD284
Gene name synonimsN/A
Other gene names ARMD10, CD284, N/A, TLR-4, TLR4, TOLL, TLR4
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneHTA125
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TLR4, TLR4 is weakly expressed by resting cells, TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule, This antibody has been demonstrated to block activation of monocytes with LPS, This particular antibody might cross react with speacies outside of the listed ones, also known as CD284, but is upregulated following stimulation with LPS, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages, CD284 This item recognises the human Toll like receptor 4 (TLR4) cell surface antigen
Purification methodN/A
Form/AppearanceLow Endotoxin (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping Avoid repeated freezing and thawing as this may denature the protein, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, the antibody should be stored at -20 degrees Celsius
Tested applications: Flow Cytometry (FACS), Functional Assay (FA), Western Blot (WB), Immunoprecipitation (IP)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD284: Endotoxin
Short nameMOUSE Anti-HUMAN CD284:Low Endotoxin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD284:Low Endotoxin (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11850
Gene TLR4
Long gene name toll like receptor 4
Synonyms gene name toll-like receptor 4
Synonyms hToll CD284 TLR-4 ARMD10
Locus 9q33, 1
Discovery year 1998-06-25
GenBank acession U88880
Entrez gene record 7099
Pubmed identfication 9435236 9237759
RefSeq identity NM_138554
Classification CD molecules Toll like receptors
Havana BLAST/BLAT OTTHUMG00000021046

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