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MOUSE Anti-HUMAN CD314 Antibody

MOUSE Anti-HUMAN CD314 Antibody size: 200ug 531

Supplier MBS MONO
Price 531
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD314
Other names Killer cell lectin-like receptor subfamily K member 1, N/A, NK cell receptor D, NK cell receptor D, NKG2-D type II integral membrane protein, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2-D-activating NK receptor, killer cell lectin-like receptor subfamily K member 1, NKG2-D type II integral membrane protein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD314
Gene name synonimsN/A
Other gene names D12S2489E, KLRK1, N/A, NKG2D, KLRC4-KLRK1
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
Clone5C6
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity 3), CD314 forms homodimers that signal through an associated DAP10 adaptor protein, CD8 T cells and gamma delta T cells, Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells, MICB and UL16 binding protein (ULBP), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, _x000D__x000D_Clone 5C6 is reported to inhibit T cell recognition of MICA (1, _x000D__x000D_Ligands of CD314 include MICA, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1), which are inducibly expressed, CD314 This item is specific for CD314
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunoprecipitation (IP)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD314
Short nameMOUSE Anti-HUMAN CD314 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD314 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 18788
Gene KLRK1
Long gene name killer cell lectin like receptor K1
Synonyms gene D12S2489E
Synonyms gene name DNA segment on chromosome 12 (unique) 2489 expressed sequence killer cell lectin-like receptor subfamily K, member 1
Synonyms NKG2D KLR NKG2-D CD314
Locus 12p13, 2
Discovery year 2003-12-12
GenBank acession AJ001687
Entrez gene record 22914
Pubmed identfication 9683661 2007850
RefSeq identity NM_007360
Classification Killer cell lectin like receptors CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000168574

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