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MOUSE Anti-HUMAN CD314:RPE Antibody

MOUSE Anti-HUMAN CD314:RPE Antibody size: 100 Tests 475

Supplier MBS MONO
Price 475
Size 100 Tests
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD314
Other names Killer cell lectin-like receptor subfamily K member 1, N/A, NK cell receptor D, NK cell receptor D, NKG2-D type II integral membrane protein, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2-D-activating NK receptor, killer cell lectin-like receptor subfamily K member 1, NKG2-D type II integral membrane protein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD314
Gene name synonimsN/A
Other gene names D12S2489E, KLRK1, N/A, NKG2D, KLRC4-KLRK1
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone1D11
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD314 forms homodimers that signal through an associated DAP10 adaptor protein, CD8 T cells and gamma delta T cells, Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells, MICB and UL16 binding protein (ULBP), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, _x000D__x000D_Clone 1D11 is reported to inhibit T cell recognition of MICA (1, _x000D__x000D_Ligands of CD314 include MICA, member 1 (KLRK1), which are inducibly expressed, 6), CD314 This item is specific for CD314 also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K
Purification methodN/A
Form/Appearance Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R
ConcentrationN/A
Storage and shipping After reconstitution Keep the antibody refrigerated at +4 degrees Celsius, DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD314:RPE
Short nameMOUSE Anti-HUMAN CD314:RPE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD314:RPE (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 18788
Gene KLRK1
Long gene name killer cell lectin like receptor K1
Synonyms gene D12S2489E
Synonyms gene name DNA segment on chromosome 12 (unique) 2489 expressed sequence killer cell lectin-like receptor subfamily K, member 1
Synonyms NKG2D KLR NKG2-D CD314
Locus 12p13, 2
Discovery year 2003-12-12
GenBank acession AJ001687
Entrez gene record 22914
Pubmed identfication 9683661 2007850
RefSeq identity NM_007360
Classification Killer cell lectin like receptors CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000168574

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