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MOUSE Anti-HUMAN CD325 Antibody

MOUSE Anti-HUMAN CD325 Antibody size: 200ug 503

Supplier MBS MONO
Price 503
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD325
Other names Cadherin-2, N-cadherin (neuronal), Neural cadherin, cadherin 2, cadherin 2, cadherin 2 type 1 N-cadherin (neuronal), cadherin-2, neural cadherin, type 1, cadherin-2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD325
Gene name synonimsN/A
Other gene names Cdh2, N-cadherin, N-cadherin, Cdh2
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone13A9
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity (neural cadherin), CD325 is directly involved in the differentiation of early hematopoietic progenitors, CD325 is expressed by neurons, Clone 13A9 has been shown to be specific for N-cadherin, M-cadherin or P-cadherin Immunohistological studies have shown that clone 13A9 can be used as a reliable marker for the differential diagnosis of pleural mesotheliomas and lung adenocarcinomas, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a calcium dependent cell-cell adhesion glycoprotein, and does not recognize E-cadherin, and is commonly expressed by cancer cells, and is one of the primary cadherins recruited to the site of neuronal synapse formation, and member of the cadherin superfamily, and plays a role in cell-matrix adhesion, and stem cells, and subsequent failure of the intercellular connection between two adjacent endothelial cells, and the establishment of left-right asymmetry, cell growth and differentiation, endothelial cells, muscle cells, otherwise known as N-cadherin, playing a role in transendothelial migration and metastasis, through the up-regulation of the src kinase pathway, when used in conjunction with E-cadherin <, which links to the actin cytoskeleton via catenins, (4-5)<, /sup>, CD325 This item specifically recognises CD325, sup>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC), Immunoprecipitation (IP), Western Blot (WB), Immunofluorescence (IF)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD325
Short nameMOUSE Anti-HUMAN CD325 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD325 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 1759
Gene CDH2
Long gene name cadherin 2
Synonyms gene NCAD
Synonyms gene name N-cadherin (neuronal) , cadherin 2, type 1
Synonyms CDHN CD325
Synonyms name N-cadherin
Locus 18q12, 1
Discovery year 1991-09-13
GenBank acession S42303
Entrez gene record 1000
Pubmed identfication 2384753 7731968 2216790
RefSeq identity NM_001792
Classification Type I classical cadherins CD molecules
Havana BLAST/BLAT OTTHUMG00000059940

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