Name : MOUSE Anti-HUMAN CD326 Antibody
Supplier : MBS MONO
Price :1144
SKU : GEN4794624217
| Also known as | CD326 |
| Other names | Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, EGP, EGP314, Epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, adenocarcinoma-associated antigen, cell surface glycoprotein Trop-1, chromosome 4, epithelial cell adhesion molecule, epithelial cell adhesion molecule, epithelial glycoprotein 314, hEGP314, human epithelial glycoprotein-2, major gastrointestinal tumor-associated protein GA733-2, membrane component, surface marker (35kD glycoprotein), tumor-associated calcium signal transducer 1, epithelial cell adhesion molecule |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD326 |
| Gene name synonims | N/A |
| Other gene names | DIAR5, EGP, EGP-2, EGP314, EGP314, EGP40, EPCAM, ESA, Ep-CAM, GA733-2, HNPCC8, KS1/4, KSA, M1S2, M4S1, M4S1, MIC18, MIC18, MK-1, TACSTD1, TACSTD1, TROP1, TROP1, hEGP314, EPCAM |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | HEA-125 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | It is expressed on the basolateral membrane of cells by the majority of epithelial tissues, MOC31 and Ber-EP4, Several monoclonal antibodies have been raised against Ep-CAM, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antigen has been identified independently by a number of groups, This particular antibody might cross react with speacies outside of the listed ones, and de novo expression being seen in dysplastic squamous epithelium, and it has been known by a variety of names including Epithelial Specific Antigen, many of which have been described as tumour specific molecules on carcinomas, with expression being increased in tumour cells, with the exception of adult squamous epithelium and some specific epithelial cell types including hepatocytes and gastric epithelial cells, CD326 This antibody recognises the 34kD cell surface antigen known as CD326 or Epithelial Cell Adhesion Molecule (Ep-CAM), _x000D__x000D_Ep-CAM expression has been reported to be a possible marker of early malignancy, _x000D__x000D_Ep-CAM is a Type 1 transmembrane glycoprotein |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | CD326 |
| Short name | MOUSE Anti-HUMAN CD326 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens CD326 (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Identity | 11529 |
| Gene | EPCAM |
| Long gene name | epithelial cell adhesion molecule |
| Synonyms gene | M4S1 MIC18 TACSTD1 |
| Synonyms gene name | antigen identified by monoclonal antibody AUA1 tumor-associated calcium signal transducer 1 |
| Synonyms | Ly74 TROP1 GA733-2 EGP34 EGP40 EGP-2 KSA CD326 Ep-CAM HEA125 KS1/4 MK-1 MH99 MOC31 323/A3 17-1A TACST-1 CO-17A ESA |
| Locus | 2p21 |
| Discovery year | 1995-10-02 |
| GenBank acession | M33011 |
| Entrez gene record | 4072 |
| Pubmed identfication | 8382772 11306819 |
| Classification | CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000128853 |
| Locus Specific Databases | Colon cancer gene variant databases LRG_215 |