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MOUSE Anti-HUMAN CD47:Low Endotoxin Antibody

MOUSE Anti-HUMAN CD47:Low Endotoxin Antibody size: 500ug 647

Supplier MBS MONO
Price 647
Size 500ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD47
Other names Antigenic surface determinant protein OA3, CD47 antigen (Rh-related antigen, CD47 glycoprotein, CD47 molecule, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, Protein MER6, Rh-related antigen, antigen identified by monoclonal antibody 1D8, antigenic surface determinant protein OA3, integrin associated protein, integrin-associated protein, integrin-associated signal transducer, integrin-associated signal transducer), leukocyte surface antigen CD47, leukocyte surface antigen CD47 isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD47
Gene name synonimsN/A
Other gene names CD47, IAP, IAP, MER6, MER6, OA3, CD47
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
Clone1/1A4
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1, CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 50kDa glycoprotein expressed on all haematopoietic cell lines, also known as integrin-associated protein, and may act as a signal transducer in the regulation of cation fluxes across cell membranes, caspase-independent apoptosis, endothelial cells, epithelial cells, fibroblasts and many tumour cell lines, regulation of neutrophil (PMN) chemotaxis, CD47 This item is specific for human CD47
Purification methodN/A
Form/AppearanceLow Endotoxin (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, only, the antibody should be stored undiluted, Store the antibody should be stored at -20 degrees Celsius
Tested applications: Functional Assay (FA), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD47: Endotoxin
Short nameMOUSE Anti-HUMAN CD47:Low Endotoxin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD47 molecule:Low Endotoxin (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Alternative to gene target CD47 and IDBG-48744 and ENSG00000196776 and 961, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, IAP and MER6 and OA3, Plasma membranes, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008228 and opsonization and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009617 and response to bacterium and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0070053: thrombospondin receptor activity, this GO :0070053: thrombospondin receptor activity, thrombospondin receptor activity, CD47 molecule
Identity 1682
Gene CD47
Long gene name CD47 molecule
Synonyms gene MER6
Synonyms gene name CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
Synonyms IAP OA3
Synonyms name antigen identified by monoclonal antibody 1D8 antigenic surface determinant protein OA3 integrin associated protein Rh-related antigen leukocyte surface antigen CD47 CD47 glycoprotein
Locus 3q13, 12
Discovery year 1994-12-12
Entrez gene record 961
Pubmed identfication 8294396 2277087
RefSeq identity NM_001777
Classification Immunoglobulin like domain containing CD molecules
Havana BLAST/BLAT OTTHUMG00000044216

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