Name : MOUSE Anti-HUMAN CD55:RPE Antibody
Supplier : MBS MONO
Price :475
SKU : GEN8726058308
| Also known as | CD55 |
| Other names | CD55 antigen, CD55 molecule, Complement decay-accelerating factor, N/A, complement decay-accelerating factor, decay accelerating factor for complement (Cromer blood group), complement decay-accelerating factor isoform 1 preproprotein |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD55 |
| Gene name synonims | N/A |
| Other gene names | CD55, CR, CR, CROM, DAF, DAF, TC, CD55 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 67 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | DAF binds to activated C4b or C3b complement fragments on the cell surface, DAF carries the Cromer related blood group antigens, DAF has a wide distribution on cells in non-haemopoietic tissues, In other cells the apparent molecular weight is somewhat larger, It has a substantial content of O-glycans, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antigen on erythrocytes is pronase and chymotrypsin sensitive, This particular antibody might cross react with speacies outside of the listed ones, and also on N-glycan, but resistant to trypsin, decay accelerating factor (DAF) It is a 70kD glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail, for example, in plasma, particularly epithelium and is specifically found at the foetal-maternal interface in placenta Soluble forms of DAF are found, preventing the assembly and accelerating the decay of both classical and alternative pathways, saliva and urine, CD55 CD55 is the complement regulatory protein |
| Purification method | N/A |
| Form/Appearance | Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R |
| Concentration | N/A |
| Storage and shipping | DO NOT FREEZE, Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | CD55:RPE |
| Short name | MOUSE Anti-HUMAN CD55:RPE Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | decay accelerating factor to measure complement (Cromer blood group):RPE (Antibody to), sapiens CD55 molecule, MOUSE antibody to-H |
| Alternative technique | antibodies |
| Alternative to gene target | CD55 and IDBG-106331 and ENSG00000196352 and 1604, CD55 and IDBG-629269 and ENSBTAG00000006984 and 518609, CR and CROM and DAF and TC, Extracellular, alpha-beta T cell activation and biological process this GO :2000563 and positive regulation of CD4-positive, alpha-beta T cell cytokine production and biological process this GO :0043086 and negative regulation of catalytic activity and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045730 and respiratory burst and biological process this GO :0045916 and negative regulation of complement activation and biological process this GO :0060137 and maternal process involved in parturition and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000516 and positive regulation of CD4-positive, alpha-beta T cell proliferation and biological process, classical pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008289 and lipid binding and molecular function this GO :0009615 and response to virus and biological process this GO :0009986 and cell surface and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0030449 and regulation of complement activation and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0031664 and regulation of lipopolysaccharide-mediated signaling pathway and biological process this GO :0035743 and CD4-positive, decay accelerating factor for complement (Cromer blood group), lipid binding, this GO :0001618 and virus receptor activity and molecular function this GO :0004857 and enzyme inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006958 and complement activation, this GO :0001618: virus receptor activity, this GO :0001618: virus receptor activity and also this GO :0004857: enzyme inhibitor activity and also this GO :0005515: protein binding and also this GO :0008289: lipid binding, this GO :0004857: enzyme inhibitor activity, this GO :0005515: protein binding, this GO :0008289: lipid binding, CD55 molecule |
| Identity | 2665 |
| Gene | CD55 |
| Long gene name | CD55 molecule (Cromer blood group) |
| Synonyms gene | DAF |
| Synonyms gene name | Cromer blood group system) CD55 molecule, decay accelerating factor for complement (CD55, decay accelerating factor for complement (Cromer blood group) |
| Synonyms | CR TC CROM |
| Locus | 1q32, 2 |
| Discovery year | 2001-06-22 |
| GenBank acession | BC001288 |
| Entrez gene record | 1604 |
| RefSeq identity | NM_000574 |
| Classification | Sushi domain containing CD molecules Blood group antigens |
| Havana BLAST/BLAT | OTTHUMG00000036255 |
| Locus Specific Databases | Blood Group Antigen Mutation Database CD55base: Mutation registry for Decay-accelerating factor (CD55) deficiency (previously known as DAFbase) LRG_127 |