Name : MOUSE Anti-HUMAN CD56:FITC Antibody
Supplier : MBS MONO
Price :448
SKU : GEN9120697151
| Also known as | CD56 |
| Other names | N/A, NCAM, Neural cell adhesion molecule 1, antigen recognized by monoclonal antibody 5, neural cell adhesion molecule, neural cell adhesion molecule 1, neural cell adhesion molecule 1, 1H11, neural cell adhesion molecule 1 isoform 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD56 |
| Gene name synonims | N/A |
| Other gene names | CD56, MSK39, N-CAM-1, NCAM, NCAM, NCAM-1, NCAM1, NCAM1 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 123C3 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Antibodies produced by clone 123C3 recognise the 140 and 180kD isoforms of the CD56 protein, CD56 is expressed in a range of tumours including tumours of the lung, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development, Neurons express the largest 180kD form, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid, The CD56 molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, This particular antibody might cross react with speacies outside of the listed ones, Three main isoforms of CD56 exist, _x000D__x000D_In neuronal tissues, natural killer cells and a subset of T cells in the peripheral blood, neural derived malignancies and natural killer cell lymphomas, otherwise known as CD56, while haemopoietic cells express the 140kD isoform, CD56 This item recognises human neural cell adhesion molecule (NCAM) |
| Purification method | N/A |
| Form/Appearance | FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation | Anti-FITC Antibody |
| Gene target | CD56: |
| Short name | MOUSE Anti-HUMAN CD56:FITC Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label | FITC |
| Alternative name | sapiens CD56:fluorecein (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Identity | 7656 |
| Gene | NCAM1 |
| Long gene name | neural cell adhesion molecule 1 |
| Synonyms | NCAM CD56 |
| Locus | 11q23, 2 |
| Discovery year | 2001-06-22 |
| Entrez gene record | 4684 |
| RefSeq identity | NM_000615 |
| Classification | Fibronectin type III domain containing I-set domain containing CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000167196 |