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MOUSE Anti-HUMAN CD58:RPE Antibody

MOUSE Anti-HUMAN CD58:RPE Antibody size: 100 Tests 475

Supplier MBS MONO
Price 475
Size 100 Tests
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD58
Other names (lymphocyte function-associated antigen 3), CD58 antigen, CD58 molecule, Lymphocyte function-associated antigen 3, Surface glycoprotein LFA-3, lymphocyte function-associated antigen 3, surface glycoprotein LFA-3, lymphocyte function-associated antigen 3 isoform 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD58
Gene name synonimsN/A
Other gene names Ag3, CD58, LFA-3, LFA3, LFA3, ag3, CD58
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneMEM-63
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD58 has a wide tissue distribution, CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes<, It is a member of the immunoglobulin superfamily of molecules, It is heavily N-glycosylated, It occurs in two forms, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The complete amino acid sequence of both forms has been deduced from cDNA, There are approximately 5, There is reduced expression of CD58 on haemopoletic cells in individuals with paroxysmal nocturnal haemoglobinuria, This particular antibody might cross react with speacies outside of the listed ones, a subset of lymphocytes, being present on erythrocytes, bone marrow cells, epithelium and endothelial cells <, is a membrane glycoprotein of 55-70kD, monocytes, one transmembrane with a cytoplasmic domain, or LFA-3, platelets, the other form anchored in the membrane via a glycosylphosphatidylinositol tail, /sup>, /sup>, 000 CD58 molecules on each erythrocyte, CD58 CD58, [1]<, [2]<, sup>, sup>
Purification methodN/A
Form/Appearance Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R
ConcentrationN/A
Storage and shipping DO NOT FREEZE, Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD58:RPE
Short nameMOUSE Anti-HUMAN CD58:RPE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD58 molecule:RPE (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Alternative to gene target CD58 and IDBG-101394 and ENSG00000116815 and 965, CD58 and IDBG-634482 and ENSBTAG00000040131 and 782186, Cell surfaces, ag3 and LFA-3 and LFA3, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :2000484 and positive regulation of interleukin-8 secretion and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, CD58 molecule
Identity 1688
Gene CD58
Long gene name CD58 molecule
Synonyms gene LFA3
Synonyms gene name (lymphocyte function-associated antigen 3) , CD58 antigen
Locus 1p13, 1
Discovery year 1989-04-06
GenBank acession BC005930
Entrez gene record 965
Pubmed identfication 9510189
RefSeq identity NM_001779
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000022749

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