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MOUSE Anti-HUMAN CD59:FITC Antibody

MOUSE Anti-HUMAN CD59:FITC Antibody size: 100ug 486

Supplier MBS MONO
Price 486
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD59
Other names 1F5 antigen, 1F5 antigen, 20 kDa homologous restriction factor, 20 kDa homologous restriction factor, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16, CD59 glycoprotein, CD59 glycoprotein, CD59 molecule, EJ16, EJ30, EL32 and G344), HRF-20, HRF20, Ly-6-like protein, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MEM43 antigen, MIRL, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin, T cell-activating protein, complement regulatory protein, human leukocyte antigen MIC11, lymphocytic antigen CD59/MEM43, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, membrane inhibitor of reactive lysis, protectin, surface anitgen recognized by monoclonal antibody 16, 3A5, 3A5, CD59 glycoprotein preproprotein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD59
Gene name synonimsN/A
Other gene names 16, 1F5, CD59, EJ16, EJ30, EL32, G344, HRF-20, HRF-20, HRF20, HRF20, MAC-IP, MAC-IP, MACIF, MACIF, MEM43, MIC11, MIC11, MIN1, MIN1, MIN2, MIN2, MIN3, MIN3, MIRL, MIRL, MSK21, MSK21, p18-20, 3A5, CD59
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneMEM-43
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antigen binds to C8 and C9 and inhibits assembly of the complement membrane attack complex, This particular antibody might cross react with speacies outside of the listed ones, expressed by virtually all cell types, including leucocytes, platelets and erythrocytes, CD59 CD59 is an 18-20kD GPI anchored single chain glycoprotein
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD59:
Short nameMOUSE Anti-HUMAN CD59:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name complement regulatory protein:fluorecein (Antibody to), sapiens CD59 molecule, MOUSE antibody to-H
Alternative techniqueantibodies
Alternative to gene target 16, CD59 and IDBG-38813 and ENSG00000085063 and 966, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574, Extracellular, complement regulatory protein, protein binding, this GO :0001775 and cell activation and biological process this GO :0001848 and complement binding and molecular function this GO :0001971 and negative regulation of activation of membrane attack complex and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0030449 and regulation of complement activation and biological process this GO :0031362 and anchored component of external side of plasma membrane and cellular component this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043218 and compact myelin and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001848: complement binding, this GO :0001848: complement binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, 3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 molecule
Identity 1689
Gene CD59
Long gene name CD59 molecule
Synonyms gene MIC11 MIN1 MSK21 MIN2 MIN3
Synonyms gene name CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16, EJ16, EJ30, EL32 and G344) CD59 antigen, complement regulatory protein , complement regulatory protein CD59 molecule, 3A5
Synonyms 16, 3A5 EJ16 EJ30 EL32 G344 p18-20
Locus 11p13
Discovery year 1989-06-30
Entrez gene record 966
Pubmed identfication 7691713
RefSeq identity NM_203329
Classification Complement system CD molecules LY6/PLAUR domain containing
Havana BLAST/BLAT OTTHUMG00000166270
Locus Specific Databases CD59base: Mutation registry for CD59 deficiency LRG_41

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