MOUSE Anti-HUMAN CD61:Biotin Antibody

MOUSE Anti-HUMAN CD61:Biotin Antibody size: 100ug 486

Price 486

Size 100ug

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Also known as	CD61
Other names	Integrin beta-3, Platelet membrane glycoprotein IIIa, antigen CD61), beta 3 (platelet glycoprotein IIIa, integrin, integrin beta-3, platelet membrane glycoprotein IIIa, integrin beta-3
Category	Antibodies
Subcategory	Mnoclonal antibodies
Gene name	CD61
Gene name synonims	N/A
Other gene names	BDPLT2, CD61, GP3A, GP3A, GPIIIa, GPIIIa, GT, ITGB3, ITGB3
Clonality	Monoclonal
Immunoglobulin isotype	IgG1
Clone	PM6/13
Host organism	Mouse (Mus musculus)
Species reactivity	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity	CD61 is a receptor for fibrinogen, CD61 is expressed on platelets and megakaryocytes in association with CD41, Clone PM6/13 has been reported to inhibit binding of fibronectin to activated human platelets, In functional studies it can be used to inhibit agonist induced platelet aggregation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This molecule associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface, This particular antibody might cross react with speacies outside of the listed ones, and on endothelial cells, fibronectin, monocytes, platelets and osteoclasts in association with CD51, vWF, vitronectin and thrombospondin, which is the integrin beta 3 chain, CD61 This item recognises a 105kD glycoprotein
Purification method	N/A
Form/Appearance	Biotin (Purified IgG conjugated to Biotin - liquid)
Concentration	1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping	If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:	Flow Cytometry (FACS)
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Conjugation	Biotinylated
Gene target	CD61:
Short name	MOUSE Anti-HUMAN CD61: Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Label	Biotin
Alternative name	sapiens CD61:biotinilated (Antibody to), MOUSE antibody to-H
Alternative technique	antibodies
Identity	6156
Gene	ITGB3
Long gene name	integrin subunit beta 3
Synonyms gene	GP3A
Synonyms gene name	antigen CD61) , beta 3 (platelet glycoprotein IIIa, integrin
Synonyms	CD61 GPIIIa
Synonyms name	platelet glycoprotein IIIa antigen CD61
Locus	17q21, 32
Discovery year	1988-06-09
Entrez gene record	3690
Pubmed identfication	2454952
RefSeq identity	NM_000212
Classification	Integrin beta subunits CD molecules
Havana BLAST/BLAT	OTTHUMG00000171956
Locus Specific Databases	LRG_481

MOUSE Anti-HUMAN CD61:Biotin Antibody

MOUSE Anti-HUMAN CD61:Biotin Antibody size: 100ug 486

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