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MOUSE Anti-HUMAN CD62L:FITC Antibody

MOUSE Anti-HUMAN CD62L:FITC Antibody size: 100ug 807

Supplier MBS MONO
Price 807
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD62L
Other names CD62 antigen-like family member L, CD62 antigen-like family member L, L-selectin, L-selectin, LAM-1, LECAM1, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, TQ1, gp90-MEL, gp90-MEL, leukocyte surface antigen Leu-8, leukocyte-endothelial cell adhesion molecule 1, lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, selectin L, L-selectin
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD62L
Gene name synonimsN/A
Other gene names CD62L, LAM-1, LAM1, LECAM1, LECAM1, LEU8, LNHR, LNHR, LSEL, LYAM1, LYAM1, PLNHR, SELL, TQ1, SELL
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
CloneFMC46
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Human CD62L is constitutively expressed on most leucocytes including monocytes, NK cells, Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naï, _x000D__x000D_The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation, a 74-95kDa member of the selectin family of adhesion receptors, also known a L-selectin, bone marrow myeloid progenitor cells and on a subset of thymocytes, but surface expression still remains, granulocytes, lymphocytes, where CD62L is rapidly shed as soluble L-selectin, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin), CD62L This item recognizes human CD62L, ve lymphocytes to lymph nodes and Peyers patches via HEV
Purification methodN/A
Form/Appearance), FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD62L:
Short nameMOUSE Anti-HUMAN CD62L:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name sapiens CD62L:fluorecein (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 10720
Gene SELL
Long gene name selectin L
Synonyms gene LYAM1 LNHR
Synonyms gene name lymphocyte adhesion molecule 1
Synonyms LSEL LAM1 LAM-1 hLHRc Leu-8 Lyam-1 PLNHR CD62L
Locus 1q24, 2
Discovery year 1989-06-07
GenBank acession M25280
Entrez gene record 6402
Pubmed identfication 2664786 1375831
RefSeq identity NM_000655
Classification Sushi domain containing Selectins CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000034809

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