MOUSE Anti-HUMAN CD62L:RPE Antibody

MOUSE Anti-HUMAN CD62L:RPE Antibody size: 100 Tests 475

Price 475

Size 100 Tests

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Also known as	CD62L
Other names	CD62 antigen-like family member L, CD62 antigen-like family member L, L-selectin, L-selectin, LAM-1, LECAM1, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, TQ1, gp90-MEL, gp90-MEL, leukocyte surface antigen Leu-8, leukocyte-endothelial cell adhesion molecule 1, lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, selectin L, L-selectin
Category	Antibodies
Subcategory	Mnoclonal antibodies
Gene name	CD62L
Gene name synonims	N/A
Other gene names	CD62L, LAM-1, LAM1, LECAM1, LECAM1, LEU8, LNHR, LNHR, LSEL, LYAM1, LYAM1, PLNHR, SELL, TQ1, SELL
Clonality	Monoclonal
Immunoglobulin isotype	IgG2b
Clone	FMC46
Host organism	Mouse (Mus musculus)
Species reactivity	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity	Human CD62L is constitutively expressed on most leucocytes including monocytes, NK cells, Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naï, _x000D__x000D_The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation, a 74-95kDa member of the selectin family of adhesion receptors, also known a L-selectin, bone marrow myeloid progenitor cells and on a subset of thymocytes, but surface expression still remains, granulocytes, lymphocytes, where CD62L is rapidly shed as soluble L-selectin, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin), CD62L This item recognizes human CD62L, ve lymphocytes to lymph nodes and Peyers patches via HEV
Purification method	N/A
Form/Appearance	Phycoerythrin (RPE) - lyophilised, ), RPE (Purified IgG conjugated to R
Concentration	N/A
Storage and shipping	DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:	Flow Cytometry (FACS)
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene target	CD62L:RPE
Short name	MOUSE Anti-HUMAN CD62L:RPE Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	sapiens CD62L:RPE (Antibody to), MOUSE antibody to-H
Alternative technique	antibodies
Identity	10720
Gene	SELL
Long gene name	selectin L
Synonyms gene	LYAM1 LNHR
Synonyms gene name	lymphocyte adhesion molecule 1
Synonyms	LSEL LAM1 LAM-1 hLHRc Leu-8 Lyam-1 PLNHR CD62L
Locus	1q24, 2
Discovery year	1989-06-07
GenBank acession	M25280
Entrez gene record	6402
Pubmed identfication	2664786 1375831
RefSeq identity	NM_000655
Classification	Sushi domain containing Selectins CD molecules C-type lectin domain containing
Havana BLAST/BLAT	OTTHUMG00000034809

MOUSE Anti-HUMAN CD62L:RPE Antibody

MOUSE Anti-HUMAN CD62L:RPE Antibody size: 100 Tests 475

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