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MOUSE Anti-HUMAN CD8:Biotin Antibody

MOUSE Anti-HUMAN CD8:Biotin Antibody size: 100ug 475

Supplier MBS MONO
Price 475
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD8
Other names CD8 antigen, CD8a molecule, Leu2 T-lymphocyte antigen, OKT8 T-cell antigen, T cell co-receptor, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, T-lymphocyte differentiation antigen T8/Leu-2, T8 T-cell antigen, alpha polypeptide (p32), T-cell surface glycoprotein CD8 alpha chain isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD8
Gene name synonimsN/A
Other gene names CD8, CD8A, Leu2, MAL, MAL, p32, CD8A
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneLT8
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity It is also expressed weakly on NK cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD8 antigen is a co-receptor for MHC Class I in conjunction with the T cell receptor, This particular antibody might cross react with speacies outside of the listed ones, and is important in the selection process of CD8+ MHC Class I restricted T cells, CD8 This item recognises the human CD8 cell surface glycoprotein expressed by a subset of peripheral blood T cells which express cytotoxic/suppressor activity
Purification methodN/A
Form/AppearanceBiotin (Purified IgG conjugated to Biotin - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationBiotinylated
Description This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity, Cytotoxic T cells cluster differentiators for flow cytometry
Gene targetCD8:
Short nameMOUSE Anti-HUMAN CD8: Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelBiotin
Alternative name sapiens CD8:biotinilated (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 1706
Gene CD8A
Long gene name CD8a molecule
Synonyms gene CD8
Synonyms gene name CD8 antigen, alpha polypeptide (p32) T-cell surface glycoprotein CD8 alpha chain
Locus 2p11, 2
Discovery year 1986-01-01
Entrez gene record 925
Pubmed identfication 1541829
RefSeq identity NM_001768
Classification CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000130265
Locus Specific Databases CD8Abase: Mutation registry for CD8 deficiency LRG_44

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