Name : MOUSE Anti-HUMAN CD80:FITC Antibody
Supplier : MBS MONO
Price :448
SKU : GEN9122775658
| Also known as | CD80 |
| Other names | Activation B7-1 antigen, B-lymphocyte activation antigen B7, B7-1 antigen), BB1, CD80 antigen (CD28 antigen ligand 1, CD80 molecule, CTLA-4 counter-receptor B7, CTLA-4 counter-receptor B7, T-lymphocyte activation antigen CD80, T-lymphocyte activation antigen CD80, activation B7-1 antigen, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, 1, 1, T-lymphocyte activation antigen CD80 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD80 |
| Gene name synonims | N/A |
| Other gene names | B7, B7, B7, B7-1, BB1, CD28LG, CD28LG, CD28LG1, CD28LG1, CD80, LAB7, LAB7, 1, CD80 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | MEM-233 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | CD80 is expressed by activated B cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, also known as B7-1, and is important in B cell - T cell interactions, being a ligand of CD28 and CD152 (CTLA-4), CD80 This item recognises the human CD80 cell surface antigen |
| Purification method | N/A |
| Form/Appearance | FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation | Anti-FITC Antibody |
| Gene target | CD80: |
| Short name | MOUSE Anti-HUMAN CD80:FITC Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label | FITC |
| Alternative name | sapiens CD80 molecule:fluorecein (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Alternative to gene target | B7 and B7-1 and B7, BT, CD80 and IDBG-51287 and ENSG00000121594 and 941, Cd80 and IDBG-160288 and ENSMUSG00000075122 and 12519, Cell surfaces, DNA-templated and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process, coreceptor activity, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045425 and positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process and biological process this GO :0045627 and positive regulation of T-helper 1 cell differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0015026: coreceptor activity, this GO :0015026: coreceptor activity, 1 and BB1 and CD28LG and CD28LG1 and LAB7, 27986 and IDBG-632750 and ENSBTAG00000018059 and 407131, CD80 molecule |
| Identity | 1700 |
| Gene | CD80 |
| Long gene name | CD80 molecule |
| Synonyms gene | CD28LG CD28LG1 |
| Synonyms gene name | B7-1 antigen) CD80 molecule , CD80 antigen (CD28 antigen ligand 1 |
| Synonyms | B7, 1 B7-1 |
| Synonyms name | B-lymphocyte activation antigen B7 |
| Locus | 3q13, 33 |
| Discovery year | 1993-12-14 |
| Entrez gene record | 941 |
| Pubmed identfication | 1370389 |
| RefSeq identity | NM_005191 |
| Classification | C2-set domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000159419 |