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MOUSE Anti-HUMAN COMPLEMENT FACTOR I Antibody

MOUSE Anti-HUMAN COMPLEMENT FACTOR I Antibody size: 100ug 658

Supplier MBS MONO
Price 658
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCOMPLEMENT FACTOR I
Other names C3B/C4B inactivator, C3B/C4B inactivator, C3b-inactivator, Complement factor I, Konglutinogen-activating factor, complement component I, complement control protein factor I, complement factor I, complement factor I, complement factor I heavy chain, light chain of factor I, complement factor I preproprotein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name AHUS3, C3BINA, C3b-INA, CFI, FI, IF, IF, KAF, CFI
Gene name synonims AHUS3, C3BINA, C3b-INA, CFI, FI, IF, IF, KAF, CFI
Other gene names AHUS3, C3BINA, C3b-INA, CFI, FI, IF, IF, KAF, CFI
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone3R/8
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity , C3b cleavage requires the presence of cofactors complement component (3b/4b) receptor 1 (CR1), Defects in CFI are also associated with haemolytic uraemic syndrome, Factor I has no natural inhibitors, Factor I is a serine protease which inactivates complement components C3b and C4b, Factor I is an 88 kDa protein consisting of one polypeptide chain of 35, Removal of Sodium Azide is recommended prior to use in functional assays, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Dysfunctional factor I can lead to uncontrolled activation of the alternative complement pathway causing in systemic depletion of C3 and lower levels of factors B and H, _x000D__x000D_This item blocks function of complement factor I, a member of the peptidase S1 family present in the blood plasma, membrane cofactor protein or factor H, resulting in recurrent pyogenic infections, while C4b cleavage requires complement component 4 binding protein or CR1, 4 kDa and one of 27, 6 kDa, COMPLEMENT FACTOR I This item recognises complement factor I
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: ELISA (EIA), Functional Assay (FA), Immunohistology - Frozen (IHC), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCOMPLEMENT FACTOR I
Short nameMOUSE Anti-HUMAN COMPLEMENT FACTOR I Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens COMPLEMENT FACTOR I (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 5394
Gene CFI
Long gene name complement factor I
Synonyms gene IF
Synonyms gene name I factor (complement)
Synonyms FI C3b-INA KAF
Synonyms name Konglutinogen-activating factor C3b-inactivator
Locus 4q25
Discovery year 1986-01-01
GenBank acession J02770
Entrez gene record 3426
Pubmed identfication 2956252
RefSeq identity NM_000204
Classification Complement system
Havana BLAST/BLAT OTTHUMG00000161109
Locus Specific Databases CFIbase: Mutation registry for Factor I deficiency (previously known as IFbase) LRG_48

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