Name : MOUSE Anti-HUMAN CYTOCHROME C Antibody
Supplier : MBS MONO
Price :569
SKU : GEN3536217529
| Also known as | CYTOCHROME C |
| Other names | Cytochrome c, N/A, cytochrome c, cytochrome c, somatic, cytochrome c |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CYC, CYC, CYCS, HCS, THC4, CYCS |
| Gene name synonims | CYC, CYC, CYCS, HCS, THC4, CYCS |
| Other gene names | CYC, CYC, CYCS, HCS, THC4, CYCS |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 2G8 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Removal of sodium azide is recommended prior to use in functional assays -, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_A second major function for cytochrome c is its role as an intermediate in apoptosis, _x000D__x000D__x000D_Clone 2G8 is reported to block the role of cytochrome c as a co-factor in the activation of caspase 9, an evolutionarily conserved protein which acts as an essential mitochondrial electron carrier between respirable substrates and oxygen, and its association with apoptotic protease activating factor 1 (Apaf-1), both through its association with inositol-3-phosphate receptor (IP3 receptor) which acts as an ER calcium release channel, during aerobic energy production, originally termed Apaf-2, resulting in the formation of the apoptosome protein complex which then recruits and activates pro-caspase 9 (Apaf-3), CYTOCHROME C This item recognises cytochrome c |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 0mg/ml, IgG concentration 1 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS), ELISA (EIA) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | CYTOCHROME C |
| Short name | MOUSE Anti-HUMAN CYTOCHROME C Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens CYTOCHROME C (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Identity | 24382 |
| Gene | COX8C |
| Long gene name | cytochrome c oxidase subunit 8C |
| Synonyms gene name | cytochrome c oxidase subunit VIIIC |
| Synonyms | COX8-3 |
| Synonyms name | cytochrome c oxidase subunit VIII isoform 3 |
| Locus | 14q32, 12 |
| Discovery year | 2004-03-24 |
| GenBank acession | AY161004 |
| Entrez gene record | 341947 |
| Pubmed identfication | 12909344 |
| RefSeq identity | NM_182971 |
| Classification | Mitochondrial complex IV: cytochrome c oxidase subunits |
| Havana BLAST/BLAT | OTTHUMG00000171279 |