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MOUSE Anti-HUMAN DECTIN-1:FITC Antibody

MOUSE Anti-HUMAN DECTIN-1:FITC Antibody size: 100ug 448

Supplier MBS MONO
Price 448
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asDECTIN-1
Other names Beta-glucan receptor, C-type (calcium dependent, C-type lectin domain family 7, C-type lectin domain family 7 member A, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, C-type lectin superfamily member 12, DC-associated C-type lectin 1, Dendritic cell-associated C-type lectin 1, beta-glucan receptor, carbohydrate-recognition domain) lectin, dectin-1, dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, lectin-like receptor 1, member A, superfamily member 12, C-type lectin domain family 7 member A isoform b
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name BGR, BGR, CANDF4, CLEC7A, CLECSF12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, DECTIN1, Dectin-1, CLEC7A
Gene name synonims BGR, BGR, CANDF4, CLEC7A, CLECSF12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, DECTIN1, Dectin-1, CLEC7A
Other gene names BGR, BGR, CANDF4, CLEC7A, CLECSF12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, DECTIN1, Dectin-1, CLEC7A
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneGE2
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity ?GR-A and ?GR-B differs by the presence and absence, Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, Clone GE2 could be used to inhibit receptor function, Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response, It is a major pathogen pattern-recognition receptor that binds beta-glucans, It is highly expressed on peripheral blood leukocytes and dendritic cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This item (clone GE2) recognises both of these isoforms, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Human Dectin-1 has two major (?GR-A and ?GR-B) and several minor isoforms, a C-type lectin domain family member, also known as beta-glucan receptor (?GR), as well as tumor formation, fungi and some bacteria, glucose polymers that form cell-wall components or exopolymers of yeasts, of a stalk region, respectively, viral and protozoan infections, yeast, DECTIN-1 This item recognises human Dectin-1
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetDECTIN-1:
Short nameMOUSE Anti-HUMAN DECTIN-1:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative name sapiens DECTIN-1:fluorecein (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 14558
Gene CLEC7A
Long gene name C-type lectin domain family 7 member A
Synonyms gene CLECSF12
Synonyms gene name C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 12 C-type lectin domain family 7
Synonyms dectin-1 hDectin-1 CD369 SCARE2
Locus 12p13, 2
Discovery year 2001-02-01
GenBank acession AY009090
Entrez gene record 64581
RefSeq identity NM_197954
Classification CD molecules Scavenger receptors C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000133597
Locus Specific Databases LRG_179

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