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MOUSE Anti-HUMAN DECTIN-1:RPE Antibody

MOUSE Anti-HUMAN DECTIN-1:RPE Antibody size: 100 Tests 475

Supplier MBS MONO
Price 475
Size 100 Tests
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asDECTIN-1
Other names Beta-glucan receptor, C-type (calcium dependent, C-type lectin domain family 7, C-type lectin domain family 7 member A, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, C-type lectin superfamily member 12, DC-associated C-type lectin 1, Dendritic cell-associated C-type lectin 1, beta-glucan receptor, carbohydrate-recognition domain) lectin, dectin-1, dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, lectin-like receptor 1, member A, superfamily member 12, C-type lectin domain family 7 member A isoform b
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name BGR, BGR, CANDF4, CLEC7A, CLECSF12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, DECTIN1, Dectin-1, CLEC7A
Gene name synonims BGR, BGR, CANDF4, CLEC7A, CLECSF12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, DECTIN1, Dectin-1, CLEC7A
Other gene names BGR, BGR, CANDF4, CLEC7A, CLECSF12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, DECTIN1, Dectin-1, CLEC7A
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneGE2
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity ?GR-A and ?GR-B differs by the presence and absence, Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, Clone GE2 could be used to inhibit receptor function, Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response, It is a major pathogen pattern-recognition receptor that binds beta-glucans, It is highly expressed on peripheral blood leukocytes and dendritic cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This item (clone GE2) recognises both of these isoforms, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Human Dectin-1 has two major (?GR-A and ?GR-B) and several minor isoforms, a C-type lectin domain family member, also known as beta-glucan receptor (?GR), as well as tumor formation, fungi and some bacteria, glucose polymers that form cell-wall components or exopolymers of yeasts, of a stalk region, respectively, viral and protozoan infections, yeast, DECTIN-1 This item recognises human Dectin-1
Purification methodN/A
Form/Appearance Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R
ConcentrationN/A
Storage and shipping After reconstitution Keep the antibody refrigerated at +4 degrees Celsius, DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetDECTIN-1:RPE
Short nameMOUSE Anti-HUMAN DECTIN-1:RPE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens DECTIN-1:RPE (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 14558
Gene CLEC7A
Long gene name C-type lectin domain family 7 member A
Synonyms gene CLECSF12
Synonyms gene name C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 12 C-type lectin domain family 7
Synonyms dectin-1 hDectin-1 CD369 SCARE2
Locus 12p13, 2
Discovery year 2001-02-01
GenBank acession AY009090
Entrez gene record 64581
RefSeq identity NM_197954
Classification CD molecules Scavenger receptors C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000133597
Locus Specific Databases LRG_179

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