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MOUSE Anti-HUMAN ESTROGEN RECEPTOR ALPHA Antibody

MOUSE Anti-HUMAN ESTROGEN RECEPTOR ALPHA Antibody size: 1 mililiter 1691

Supplier MBS MONO
Price 1691
Size 1 mililiter
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asESTROGEN RECEPTOR ALPHA
Other names ER-alpha, ER-alpha, Estradiol receptor, Estrogen receptor, Nuclear receptor subfamily 3 group A member 1, estradiol receptor, estrogen nuclear receptor alpha, estrogen receptor, estrogen receptor 1, estrogen receptor alpha 3*, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha delta 3*, estrogen receptor alpha delta 3*, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*, estrogen receptor alpha delta 4*, nuclear receptor subfamily 3 group A member 1, 4, 4, 4, 5, 5, 5, 5, 5, 6, 6, 6, 6, 6, 7, 7*, 7*/654 isoform, 7*/819-2 isoform, 7*/822 isoform, 8*/901 isoform, 8*/941 isoform, estrogen receptor
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name ER, ER, ESR, ESR, ESR1, ESRA, Era, NR3A1, NR3A1, ESR1
Gene name synonims ER, ER, ESR, ESR, ESR1, ESRA, Era, NR3A1, NR3A1, ESR1
Other gene names ER, ER, ESR, ESR, ESR1, ESRA, Era, NR3A1, NR3A1, ESR1
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone6F11
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Approximately 75% to 80% of breast tumors have estrogen and/or progesterone receptors, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The detection of estrogen (ER) and progesterone (PR) receptors using immunohistochemical staining of formal fixed paraffin embedded (FFPE) tissue, This particular antibody might cross react with speacies outside of the listed ones, and the presence of these receptors helps determine both the patient's prognosis and the effectiveness of hormonal therapy , has gradually replaced ligand binding assays (LBA), to become the most common method for the determination of the ER/PR status of breast tumors, ESTROGEN RECEPTOR ALPHA Clone 6F11 recognises the human estrogen receptor alpha chain
Purification methodN/A
Form/AppearanceS/N (Tissue Culture Supernatant - lyophilised)
ConcentrationN/A
Storage and shipping Following reconstitution Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, the antibody should be stored undiluted Storage in frost free freezers is not recommended, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius
Tested applications: Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetESTROGEN RECEPTOR ALPHA
Short nameMOUSE Anti-HUMAN ESTROGEN RECEPTOR ALPHA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens ESTROGEN RECEPTOR a (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 3471
Gene ESRRA
Long gene name estrogen related receptor alpha
Synonyms gene ESRL1
Synonyms ERR1 ERRalpha NR3B1 ERRa
Locus 11q13, 1
Discovery year 1997-04-25
GenBank acession X51416 L38487
Entrez gene record 2101
Pubmed identfication 3267207
RefSeq identity NM_004451
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000150641

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