Filters

MOUSE Anti-HUMAN LOX-1 (SOLUBLE) Antibody

MOUSE Anti-HUMAN LOX-1 (SOLUBLE) Antibody size: 200ug 503

Supplier MBS MONO
Price 503
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asLOX-1
Other names C-type lectin domain family 8 member A, C-type lectin domain family 8 member A, LOX-1, Lectin-like oxLDL receptor 1, Lectin-like oxidized LDL receptor 1, Lectin-type oxidized LDL receptor 1, Oxidized low-density lipoprotein receptor 1, hLOX-1, hLOX-1, lectin-type oxidized LDL receptor 1, member 1, ox LDL receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, scavenger receptor class E, soluble form, oxidized low-density lipoprotein receptor 1 isoform 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameLOX-1
Gene name synonimsN/A
Other gene names CLEC8A, CLEC8A, LOX-1, LOX1, LOX1, LOXIN, Lectin-like oxLDL receptor 1, OLR1, Ox-LDL receptor 1, SCARE1, SLOX1, hLOX-1, OLR1
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneLOX19-22
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity It can be cleaved by an unknown protease at the extracellular juxtamembrane region to release the soluble form (aa58-273) of LOX-1, It is a Type II membrane protein with a typical C-type lectin structure at the extracellular C-terminus which recognises the ligand, LOX-1 activation by oxidised LDL causes endothelial changes such as decreased nitric oxide release and an increased expression of adhesion molecules, LOX-1 also binds activated platelets and apoptotic cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The expression of LOX-1 is induced by proatherogenic conditions such as hyperlipidemia, This particular antibody might cross react with speacies outside of the listed ones, This receptor mediates the recognition, a 31kDa protein of the C-type lectin superfamily, hypertension and diabetes and as such appears to contribute to the pathogenesis of vascular disorders, internalisation and degradation of oxidised LDL, particularly atherosclerosis, recognised by This item, LOX-1 This item recognises the lectin-like oxidised low-density lipoprotein (LDL) receptor (LOX-1)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Western Blot (WB), ELISA (EIA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetLOX-1 (SOLUBLE)
Short nameMOUSE Anti-HUMAN LOX-1 (SOLUBLE) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens LOX-1 (SOLUBLE) (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 8133
Gene OLR1
Long gene name oxidized low density lipoprotein receptor 1
Synonyms gene name oxidised low density lipoprotein (lectin-like) receptor 1
Synonyms LOX-1 SCARE1 CLEC8A
Locus 12p13, 2
Discovery year 1998-01-16
GenBank acession D89050
Entrez gene record 4973
Pubmed identfication 9763655
RefSeq identity NM_002543
Classification Scavenger receptors C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000168527

Similar products

Subscribe to our Newsletter