MOUSE Anti-HUMAN NQO1:HRP Antibody

MOUSE Anti-HUMAN NQO1:HRP Antibody size: 100ug 393

Price 393

Size 100ug

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Also known as	NQO1
Other names	Azoreductase, DT-diaphorase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H dehydrogenase, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, Phylloquinone reductase, Quinone reductase 1, azoreductase, diaphorase (NADH/NADPH) (cytochrome b-5 reductase), diaphorase-4, dioxin-inducible 1, menadione reductase, phylloquinone reductase, quinone 1, quinone reductase 1, NAD(P)H dehydrogenase
Category	Antibodies
Subcategory	Mnoclonal antibodies
Gene name	NQO1
Gene name synonims	N/A
Other gene names	DHQU, DIA4, DIA4, DTD, DTD, NMOR1, NMOR1, NMORI, NQO1, QR1, QR1, NQO1
Clonality	Monoclonal
Immunoglobulin isotype	IgG1
Clone	A180
Host organism	Mouse (Mus musculus)
Species reactivity	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity	Mutations in the NQO1 gene are associated with an increased risk of certain cancers, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ability of NQO1 to bioactivate anti-tumour quinones including mitomycin C and diaziquone, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone A180 detects endogenous levels of total NQO1, _x000D__x000D_Clone A180 is reported as suitable for use in immunofluorescence studies, _x000D__x000D_NQO1 is expressed in a wide range of tissues and is overexpressed in many human tumours including lung, a 31kDa cytosolic flavoenzyme and member of the NAD(P)H dehydrogenase (quinone) family, and an increased risk of leukaemia has been associated with diminished NQO1 activity and the NQO1 <, and does not cross-react with NQO2, brain, colon and breast, has become a focus area for chemotherapeutic studies, involved in detoxification, liver, which catalyzes the two-electron reduction of quinones to hydroquinones, *<, /sup>, 2 allele, NQO1 This item specifically recognises human NQO1 (NAD(P)H:quinone oxidoreductase 1), sup>
Purification method	N/A
Form/Appearance	HRP (Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid)
Concentration	0mg/ml, IgG concentration 1
Storage and shipping	If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:	Western Blot (WB), Immunohistology - Paraffin (IHC)
Properties	Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase
Conjugation	HRP Conjugated
Gene target	NQO1:
Short name	MOUSE Anti-HUMAN NQO1: Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Label	HRP
Alternative name	quinone 1:horseradish peroxidase (Antibody to), sapiens Nicotinamide adenine dinucleotide(P)H dehydrogenase, MOUSE antibody to-H
Alternative technique	antibodies
Alternative to gene target	Cytoplasm, DHQU and DIA4 and DTD and NMOR1 and NMORI and QR1, NQO1 and IDBG-39427 and ENSG00000181019 and 1728, NQO1 and IDBG-634590 and ENSBTAG00000020632 and 519632, Nqo1 and IDBG-190808 and ENSMUSG00000003849 and 18104, acting on NAD(P)H, acting on NAD(P)H and also this GO :0004784: superoxide dismutase activity and also this GO :0005515: protein binding and also this GO :0016491: oxidoreductase activity and also this GO :0044822: poly(A) RNA binding, acting on NAD(P)H and molecular function this GO :0004784 and superoxide dismutase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006801 and superoxide metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007271 and synaptic transmission, cholinergic and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0009636 and response to toxic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0019430 and removal of superoxide radicals and biological process this GO :0032355 and response to estradiol and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043086 and negative regulation of catalytic activity and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045471 and response to ethanol and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, cytochrome-b5 reductase activity, quinone 1, this GO :0003955 and NAD(P)H dehydrogenase (quinone) activity and molecular function this GO :0004128 and cytochrome-b5 reductase activity, this GO :0003955: NAD(P)H dehydrogenase (quinone) activity, this GO :0003955: NAD(P)H dehydrogenase (quinone) activity and also this GO :0004128: cytochrome-b5 reductase activity, this GO :0004128: cytochrome-b5 reductase activity, this GO :0004784: superoxide dismutase activity, this GO :0005515: protein binding, this GO :0016491: oxidoreductase activity, this GO :0044822: poly(A) RNA binding, NAD(P)H dehydrogenase
Identity	2874
Gene	NQO1
Long gene name	NAD(P)H quinone dehydrogenase 1
Synonyms gene	NMOR1 DIA4
Synonyms gene name	diaphorase (NADH/NADPH) (cytochrome b-5 reductase) NAD(P)H dehydrogenase, quinone 1
Synonyms	DHQU QR1 DTD
Locus	16q22, 1
Discovery year	2001-06-22
GenBank acession	M81600
Entrez gene record	1728
Pubmed identfication	2843525
Havana BLAST/BLAT	OTTHUMG00000137575

MOUSE Anti-HUMAN NQO1:HRP Antibody

MOUSE Anti-HUMAN NQO1:HRP Antibody size: 100ug 393

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