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MOUSE Anti-HUMAN PI-9 Antibody

MOUSE Anti-HUMAN PI-9 Antibody size: 100ug 365

Supplier MBS MONO
Price 365
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asPI-9
Other names CAP-3, CAP3, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, Serpin B9, clade B, clade B (ovalbumin), clade B (ovalbumin), cytoplasmic antiproteinase 3, member 9, member 9, member 9, peptidase inhibitor 9, protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, serpin B9, serpin peptidase inhibitor, serpin peptidase inhibitor, serpin B9
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene namePI-9
Gene name synonimsN/A
Other gene names CAP-3, CAP-3, CAP3, CAP3, PI-9, PI-9, PI9, PI9, SERPINB9, SERPINB9
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone7D8
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Clone 7D8 detects a band of approximately 42kDa under reducing conditions, Clone 7D8 is suitable for use in indirect Immunofluorescence, Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, PI-9, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, This particular antibody might cross react with speacies outside of the listed ones, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), also known as SerpinB9, and to a lesser extent in B cells and myeloid cells, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, monocyte-derived dendritic cells (DCs), natural killer (NK) cells, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, through cleavage of various cytoplasmic or nuclear proteins, triggers grB-mediated apoptosis, up-regulated in response to grB production and degranulation, which is endocytosed by virus-infected and malignant target cells, which may escape into the cytoplasm of the effector cells themselves, PI-9 This item is specific for human PI-9 (proteinase inhibitor 9)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetPI-9
Short nameMOUSE Anti-HUMAN PI-9 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens PI-9 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies

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