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MOUSE Anti-HUMAN PROLYL HYDROXYLASE 1 Antibody

MOUSE Anti-HUMAN PROLYL HYDROXYLASE 1 Antibody size: 100ug 393

Supplier MBS MONO
Price 393
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asPROLYL HYDROXYLASE 1
Other names Egl nine homolog 2, Estrogen-induced tag 6, HIF-PH1, HIF-prolyl hydroxylase 1, HIF-prolyl hydroxylase 1, HPH-1, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 1, Prolyl hydroxylase domain-containing protein 1, egl nine homolog 2, egl nine homolog 2 (C, elegans), estrogen-induced tag 6, hypoxia-inducible factor prolyl hydroxylase 1, prolyl hydroxylase domain-containing protein 1, egl nine homolog 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name EGLN2, EIT6, EIT6, HIF-PH1, HIF-PH1, HIF-prolyl hydroxylase 1, HIFPH1, HPH-1, HPH-1, HPH-3, PHD1, PHD1, EGLN2
Gene name synonims EGLN2, EIT6, EIT6, HIF-PH1, HIF-PH1, HIF-prolyl hydroxylase 1, HIFPH1, HPH-1, HPH-1, HPH-3, PHD1, PHD1, EGLN2
Other gene names EGLN2, EIT6, EIT6, HIF-PH1, HIF-PH1, HIF-prolyl hydroxylase 1, HIFPH1, HPH-1, HPH-1, HPH-3, PHD1, PHD1, EGLN2
ClonalityMonoclonal
Immunoglobulin isotypeIgM
ClonePHD112/G7
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity During normal oxygen conditions, Prolyl hydroxylase 1 catalyses the hydroxylation of specific prolyl residues within the HIF-1 alpha subunit, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex, _x000D__x000D_Prolyl hydroxylase 1 might also play a role in the regulation of cell growth, a 44kDa enzyme expressed abundantly in all tissues with the highest expression in testis, consisting of an alpha and beta subunit, however when hypoxia occurs this degradation is suppressed and HIF-1 activates the transcription of various genes important for survival and adaptation to hypoxia, the alpha subunit of HIF-1 is rapidly degraded, thereby targeting this subunit for degradation, which plays a key role in coordinating the cellular response to hypoxia, PROLYL HYDROXYLASE 1 This item recognises human prolyl hydroxylase 1 (PHD1)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from the date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunohistology - Paraffin (IHC), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetPROLYL HYDROXYLASE 1
Short nameMOUSE Anti-HUMAN PROLYL HYDROXYLASE 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens PROLYL HYDROXYLASE 1 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 14660
Gene EGLN2
Long gene name egl-9 family hypoxia inducible factor 2
Synonyms gene name egl nine homolog 2 (C, elegans)
Synonyms PHD1 HIFPH1
Synonyms name HIF prolyl hydroxylase 1
Locus 19q13, 2
Discovery year 2001-08-21
GenBank acession AJ310544
Entrez gene record 112398
Havana BLAST/BLAT OTTHUMG00000182703

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