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MOUSE Anti-HUMAN TRF1 Antibody

MOUSE Anti-HUMAN TRF1 Antibody size: 100ug 393

Supplier MBS MONO
Price 393
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asTRF1
Other names NIMA-interacting protein 2, NIMA-interacting protein 2, TTAGGG repeat-binding factor 1, TTAGGG repeat-binding factor 1, Telomeric protein Pin2/TRF1, Telomeric repeat-binding factor 1, telomeric protein Pin2/TRF1, telomeric repeat binding factor (NIMA-interacting) 1, telomeric repeat-binding factor 1, telomeric repeat-binding factor 1 isoform 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameTRF1
Gene name synonimsN/A
Other gene names PIN2, PIN2, TERF1, TRBF1, TRBF1, TRF, TRF, TRF1, TRF1, hTRF1-AS, t-TRF1, TERF1
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneBED5
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Additionally in conjunction with POT1 and TTAGGG repeat binding factor 1 (TRF2), Along with tankyrase-1, Clone BED5 has been reported to work in Western blotting applications, If the telomere is long enough, POT1, Protection of telomeres-1 (POT1) is a single-stranded telomeric DNA-binding protein which controls the elongation of telomeres by telomerase, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TIN2, TIN2, TPP1, TRF1 along with TRF2, TRF1 binds the double-stranded TTAGGG repeat of telomeres and regulates telomere length, TRF1 mediates the loading of POT1 onto single stranded DNA, TRF1 recruits factors to the telomere, This particular antibody might cross react with speacies outside of the listed ones, _x000D_TRF1 is thought to play a role in leukaemia being expressed at significantly higher levels in patients with acute lymphoblastic leukaemia than those with myeloid leukaemia, and PINX1, and Rap1 form the shelterin complex which distinguishes telomeres from sites of DNA damage, conveying information about telomere length to the telomere terminus, inducing the formation of the protective t-loop, telomerase is inhibited, where telomerase is regulated, TRF1 This item recognises TTAGGG repeat binding factor 1 (TRF1) a ubiquitously expressed 60kDa protein
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC), ELISA (EIA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetTRF1
Short nameMOUSE Anti-HUMAN TRF1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens TRF1 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 11728
Gene TERF1
Long gene name telomeric repeat binding factor 1
Synonyms gene TRBF1
Synonyms gene name telomeric repeat binding factor (NIMA-interacting) 1
Synonyms PIN2 TRF1 TRF
Locus 8q21, 11
Discovery year 1997-11-20
GenBank acession U74382
Entrez gene record 7013
Pubmed identfication 9391075
RefSeq identity NM_017489
Classification Shelterin complex Myb/SANT domain containing
Havana BLAST/BLAT OTTHUMG00000164522

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