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MOUSE Anti-LIPOPROTEIN LIPASE Antibody

MOUSE Anti-LIPOPROTEIN LIPASE Antibody size: 200ug 475

Supplier MBS MONO
Price 475
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asLIPOPROTEIN LIPASE
Other names Lipoprotein lipase, N/A, lipoprotein lipase, lipoprotein lipase<, lipoprotein lipase
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name LPL, LPL, N/A, LPL
Gene name synonims LPL, LPL, N/A, LPL
Other gene names LPL, LPL, N/A, LPL
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone5D2
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Bovine
Specificity and cross-reactivity Clone 5D2 has been shown to inhibit the activity of human LPL<, LPL receptor, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_A deficiency of LPL can result in hypertriglyceridemia, _x000D__x000D_Clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, a member of the AB hydrolase superfamily, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and binds to LPL sequences involved in LPL, and heparin interactions, and in particular the relationship between LPL and apolipoprotein E (ApoE), and is widely used in human studies, and many studies have focused on the critical role which LPL plays in the pathogenesis of atherosclerosis, and the release of free fatty acids into peripheral tissues, both of which are secreted in significant amounts by macrophages in developing arterial wall lesions, which plays a pivotal role in lipoprotein metabolism and transport, (2, /sup>, 3)<, LIPOPROTEIN LIPASE This item specifically recognises an epitope within amino acids 380-410 of lipoprotein lipase (LPL), sup>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetLIPOPROTEIN LIPASE
Short nameMOUSE Anti-LIPOPROTEIN LIPASE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-LIPOPROTEIN LIPASE (Antibody to)
Alternative techniqueantibodies
Identity 6620
Gene LIPD
Long gene name lipoprotein lipase
Synonyms LPL
Locus 8p21, 3
Discovery year 2001-06-22
Entrez gene record 4023
Pubmed identfication 3823907 3597382 3692485
Classification Lipases
Havana BLAST/BLAT OTTHUMG00000036645

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