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MOUSE Anti-LYN Antibody

MOUSE Anti-LYN Antibody size: 100ug 393

Supplier MBS MONO
Price 393
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asLYN
Other names Lck/Yes-related novel protein tyrosine kinase, Tyrosine-protein kinase Lyn, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, lck/Yes-related novel protein tyrosine kinase, p53Lyn, p56Lyn, tyrosine-protein kinase Lyn, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, tyrosine-protein kinase Lyn isoform B
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameLYN
Gene name synonimsN/A
Other gene names JTK8, JTK8, LYN, p53Lyn, p56Lyn, LYN
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneLYN01
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity (lyn), Once activated, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_The interaction between lyn and syk, _x000D__x000D_This chain of events involving receptor aggregation, a 56kDa member of the src family of non-receptor protein tyrosine kinases (PTKs), activation and tyrosine phosphorylation of ITAMs, following Fc epsilon R1 receptor aggregation and activation, is also vital for the survival and differentiation of B cells through the interaction of lyn and syk with the B cell receptor (BCR), is crucial for regulating the response of both mast cells and basophils, predominantly expressed in tissues of haematopoietic origin, serves as a binding site for the recruitment and activation of syk, the rapid tyrosine phosphorylation of ITAMs by lyn, triggering the phosphorylation of further adaptor and signaling molecules further down a complex signaling cascade, /sup>, LYN This item recognizes p56/p53<, lyn<, sup>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetLYN
Short nameMOUSE Anti-LYN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-LYN (Antibody to)
Alternative techniqueantibodies
Identity 6735
Gene LYN
Long gene name LYN proto-oncogene, Src family tyrosine kinase
Synonyms gene name v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Synonyms JTK8
Locus 8q12, 1
Discovery year 1986-01-01
GenBank acession M16038
Entrez gene record 4067
Pubmed identfication 3561390
RefSeq identity NM_002350
Classification SH2 domain containing Src family tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000044345

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