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Mouse Anti-Melanoma Associated Antigen Antibody

Mouse Anti-Melanoma Associated Antigen Antibody size: 100ug 409

Supplier MBS MONO
Price 409
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asMelanoma Associated Antigen
Other names N/A, melanoma-associated antigen
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameN/A
Gene name synonimsN/A
Other gene namesN/A
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneNKI-C3
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Although the antigen is associated with melanomas, Extensive further heterogeneity was geneRated in the Golgi compartment and was shown to be dependent on the presence of complex type sugars, NKI/C3 originally was described as a marker for melanoma, Recently, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antigen did show codistribution with Cathepsin D, The antigen is abundantly present in malignant melanomas, The antigen recognized by NKI/C-3 is a glycoprotein which appears as a broad band in SDS-PAGE, The antigen was shown to consist of a single protein backbone to which two or three, This particular antibody might cross react with speacies outside of the listed ones, and neuroendocrine tumors, it resurfaced as a marker to sepaRate cellular neurothekeoma from other dermal tumors in the differential diagnosis, it was not codistributed with the tyrosinase activity associated with melanogenesis, nevocellular nevi, whereas it has not been detectable in most other tissues, which is a marker for lysosomal functions, NKI/C-3 is a MAb which is directed anti a predominantly intracellular protein of Human melanoma cells, V-linked glycans were added cotranslationally
Purification methodN/A
Form/Appearance09% sodium azide, Each vial contains 100 ul 1 mg/ml purified monoclonal antibody in PBS containing 0
ConcentrationN/A
Storage and shipping or in small aliquots the antibody should be stored at -20 degrees Celsius, Store the antibody at +4 degrees Celsius
Tested applications: Immunofluorescence (IF), Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), ELISA (EIA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Test A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or 
Latin nameMus musculus
Gene targetMelanoma Associated
Short nameMouse Anti-Melanoma Associated Antigen Antibody
Technique antibodies against human proteins, antibodies for, mouses, Antibody
Species Mouses, Mouse
Alternative nameMouse antibody to-Melanoma Associated protein (Antibody to)
Alternative techniqueantibodies
Identity 29641
Gene MUM1
Long gene name melanoma associated antigen (mutated) 1
Synonyms MUM-1 EXPAND1
Locus 19p13, 3
Discovery year 2004-02-12
GenBank acession AK075241
Entrez gene record 84939
Pubmed identfication 20347427 7644523
RefSeq identity NM_032853
Classification PWWP domain containing
Havana BLAST/BLAT OTTHUMG00000180055

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