Name : MOUSE Anti-PIG SLA CLASS II DR:FITC Antibody
Supplier : MBS MONO
Price :713
SKU : GEN6935431729
| Also known as | SLA CLASS II DR |
| Other names | N/A |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | SLA CLASS II DR |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2b |
| Clone | 2E9/13 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Pig |
| Specificity and cross-reactivity | Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B, In pigs, SLA DQ and SLA DR, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, This antibody immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled porcine peripheral blood mononuclear cells, This clone reacts with lymphocytes from all outbred and miniature pigs so far tested, This item is specific for SLA DR molecules which are expressed on all B cells, This particular antibody might cross react with speacies outside of the listed ones, antigen presenting cells and on certain subsets of resting and activated T cells, suggesting that it recognises a monomorphic determinant of porcine SLA DR, this is referred to as the swine leukocyte antigen (SLA) region, SLA CLASS II DR The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections |
| Purification method | N/A |
| Form/Appearance | FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation | Anti-FITC Antibody |
| Gene target | SLA CLASS II DR: |
| Short name | MOUSE Anti-PIG SLA CLASS II DR:FITC Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label | FITC |
| Alternative name | MOUSE antibody to-swine SLA CLASS II DR:fluorecein (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30605 |
| Gene | SEPSECS |
| Long gene name | Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase |
| Synonyms | SLA/LP SLA |
| Synonyms name | soluble liver antigen/liver pancreas antigen |
| Locus | 4p15, 2 |
| Discovery year | 2007-05-01 |
| GenBank acession | AJ238617 |
| Entrez gene record | 51091 |
| Pubmed identfication | 16230358 10931155 17142313 17194211 |
| RefSeq identity | NM_016955 |
| Havana BLAST/BLAT | OTTHUMG00000128563 |