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MOUSE Anti-RAT CD252:Low Endotoxin Antibody

MOUSE Anti-RAT CD252:Low Endotoxin Antibody size: 500ug 608

Supplier MBS MONO
Price 608
Size 500ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD252
Other names OX40 ligand, OX40 ligand, Tumor necrosis factor ligand superfamily member 4, member 4, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 4, tumor necrosis factor ligand superfamily member 4
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD252
Gene name synonimsN/A
Other gene names OX40L, Ox40l, Ox40l, Tnfsf4, Txgp1, Tnfsf4
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneATM-2
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus)
Specificity and cross-reactivity CD252/OX40 interaction has been implicated in HTLV-1 associated diseases including myelopathy and adult T cell leukaemia, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone ATM-2 has been shown to block the co-stimulatory activity of CD252 on rat T cell proliferation, _x000D__x000D_The interaction of CD252 with its receptor OX40/CD134, a 22kDa type II transmembrane glycoprotein and member of the TNF superfamily, acts as a co-stimulator of T cell activation, and also by vascular endothelium, and also with the autoimmune diseases rheumatoid arthritis and inflammatory bowel disease, and is also important in activated B cell proliferation and secretion of immunoglobulins (Igs), expressed by antigen-presenting cells including activated dendritic cells and B cells, otherwise known as OX40L or CD134L, proliferation and both Th1 and Th2 cytokine production, CD252 This item specifically recognises rat CD252
Purification methodN/A
Form/AppearanceLow Endotoxin (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, only, the antibody should be stored undiluted, Store the antibody should be stored at -20 degrees Celsius
Tested applications: Functional Assay (FA), Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD252: Endotoxin
Short nameMOUSE Anti-RAT CD252:Low Endotoxin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-RAT CD252:Low Endotoxin (Antibody to)
Alternative techniqueantibodies
Identity 11934
Gene TNFSF4
Long gene name tumor necrosis factor superfamily member 4
Synonyms gene TXGP1
Synonyms gene name 34kD tumor necrosis factor (ligand) superfamily, member 4 , tax-transcriptionally activated glycoprotein 1
Synonyms OX-40L gp34 CD252
Locus 1q25, 1
Discovery year 1993-12-15
GenBank acession D90224
Entrez gene record 7292
Pubmed identfication 1996093 8076595
Classification Tumor necrosis factor superfamily CD molecules
Havana BLAST/BLAT OTTHUMG00000034838

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