| Also known as | CD4 |
| Other names | CD4 antigen, Cd4 molecule, T-cell surface antigen T4/Leu-3, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface glycoprotein CD4, W3/25 antigen, W3/25 antigen, T-cell surface glycoprotein CD4 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD4 |
| Gene name synonims | N/A |
| Other gene names | Cd4, N/A, W3/25, p55, Cd4 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | W3/25 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antibody inhibits proliferation and IL-2 production in the MLR reaction, This clone has been described reacting with paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde) This product is routinely tested in flow cytometry on rat splenocytes, This particular antibody might cross react with speacies outside of the listed ones, a 55kD molecule expressed by helper T cells and weakly by monocytes, CD4 This item recognises the rat CD4 cell surface glycoprotein |
| Purification method | N/A |
| Form/Appearance | APC (Purified IgG conjugated to Allophycocyanin (APC) - lyophilised) |
| Concentration | N/A |
| Storage and shipping | DO NOT FREEZE, Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description | GENTAUR makes custom magnetic bead couplings on 50 and 250 nm beads for certain clones, Used offer coupled to magnetic beads, CD4+ T helper cell marker or cluster differentiator of white blood cells in FACS or flow cytometry |
| Gene target | CD4 (DOMAIN 1):APC |
| Short name | MOUSE Anti-RAT CD4 (DOMAIN 1):APC Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | APC |
| Alternative name | MOUSE antibody to-RAT CD4 molecule (DOMAIN 1):adenomatous polyposis coli (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | APC and IDBG-37007 and ENSG00000134982 and 324, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT, BTPS2 and DP2 and DP2, CD4 and IDBG-15034 and ENSG00000010610 and 920, CD4 and IDBG-640247 and ENSBTAG00000003255 and 407098, CD4mut, Cd4 and IDBG-188351 and ENSMUSG00000023274 and 12504, Cell surfaces, adenomatous polyposis coli, microtubule plus-end binding, nuclei, protein homodimerization activity, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000776 and kinetochore and cellular component this GO :0001822 and kidney development and biological process this GO :0001942 and hair follicle development and biological process this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007026 and negative regulation of microtubule depolymerization and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007091 and metaphase/anaphase transition of mitotic cell cycle and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007155 and cell adhesion and biological process this GO :0007389 and pattern specification process and biological process this GO :0007409 and axonogenesis and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008017 and microtubule binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009798 and axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0019887 and protein kinase regulator activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030877 and beta-catenin destruction complex and cellular component this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0031122 and cytoplasmic microtubule organization and biological process this GO :0031253 and cell projection membrane and cellular component this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032886 and regulation of microtubule-based process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035371 and microtubule plus-end and cellular component this GO :0042483 and negative regulation of odontogenesis and biological process this GO :0042995 and cell projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043588 and skin development and biological process this GO :0044295 and axonal growth cone and cellular component this GO :0044336 and canonical Wnt signaling pathway involved in negative regulation of apoptotic process and biological process this GO :0044337 and canonical Wnt signaling pathway involved in positive regulation of apoptotic process and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045595 and regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045667 and regulation of osteoblast differentiation and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0048538 and thymus development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0051010 and microtubule plus-end binding and molecular function this GO :0051171 and regulation of nitrogen compound metabolic process and biological process this GO :0051276 and chromosome organization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060770 and negative regulation of epithelial cell proliferation involved in prostate gland development and biological process this GO :0070830 and tight junction assembly and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process, this GO :0001816 and cytokine production and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005769 and early endosome and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006948 and induction by virus of host cell-cell fusion and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007167 and enzyme linked receptor protein signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030217 and T cell differentiation and biological process this GO :0030260 and entry into host cell and biological process this GO :0031295 and T cell costimulation and biological process this GO :0032507 and maintenance of protein location in cell and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042110 and T cell activation and biological process this GO :0042289 and MHC class II protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045058 and T cell selection and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045234 and protein palmitoleylation and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process this GO :0050870 and positive regulation of T cell activation and biological process, this GO :0001948: glycoprotein binding, this GO :0001948: glycoprotein binding and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005201: extracellular matrix structural constituent and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0015026: coreceptor activity and also this GO :0019899: enzyme binding and also this GO :0019901: protein kinase binding and also this GO :0042289: MHC class II protein binding and also this GO :0042803: protein homodimerization activity, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005201: extracellular matrix structural constituent, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0008013: beta-catenin binding and also this GO :0008017: microtubule binding and also this GO :0019887: protein kinase regulator activity and also this GO :0019901: protein kinase binding and also this GO :0045295: gamma-catenin binding and also this GO :0051010: microtubule plus-end binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0008013: beta-catenin binding, this GO :0008017: microtubule binding, this GO :0008270: zinc ion binding, this GO :0015026: coreceptor activity, this GO :0019887: protein kinase regulator activity, this GO :0019899: enzyme binding, this GO :0019901: protein kinase binding, this GO :0019901: protein kinase binding, this GO :0042289: MHC class II protein binding, this GO :0042803: protein homodimerization activity, this GO :0045295: gamma-catenin binding, this GO :0051010: microtubule plus-end binding, 25770 and IDBG-644937 and ENSBTAG00000018852 and 533233, 5 and DP3 and GS and PPP1R46, CD4 molecule |
| Identity | 583 |
| Gene | APC |
| Long gene name | APC, WNT signaling pathway regulator |
| Synonyms gene name | adenomatosis polyposis coli adenomatous polyposis coli |
| Synonyms | DP2 DP3 DP2, 5 PPP1R46 |
| Synonyms name | protein phosphatase 1, regulatory subunit 46 |
| Locus | 5q22, 2 |
| Discovery year | 1986-01-01 |
| GenBank acession | M74088 |
| Entrez gene record | 324 |
| Pubmed identfication | 1651563 |
| RefSeq identity | NM_000038 |
| Classification | Protein phosphatase 1 regulatory subunits Armadillo repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000128806 |
| Locus Specific Databases | Adenomatous polyposis coli mutation database UMD Locus Specific Databases Colon cancer gene variant databases APC database at LOVD-China LOVD - Leiden Open Variation Database LRG_130 |