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MOUSE Anti-RAT CD49d Antibody

MOUSE Anti-RAT CD49d Antibody size: 0.25 miligrams 359

Supplier MBS MONO
Price 359
Size 0.25 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD49d
Other namesN/A
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD49d
Gene name synonimsN/A
Other gene namesN/A
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneMRalpha4-1
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus)
Specificity and cross-reactivity CD49d is expressed broadly on T and B lymphocytes, Clone MRalpha4-1 inhibits the <, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 150kDa type-1 transmembrane glycoprotein and member of the integrin alpha chain family, and <, and significantly inhibits the transendothelial migration of T lymphocytes, and the adhesion of cells to the extracellular matrix, clone MRalpha4-1 inhibits the rolling and adherence of lymphocytes to postcapillary venules (PCV), functions of CD49d Studies have shown that in rat Peyer's patches, mast cells and dendritic cells and is involved in cell-cell interactions, monocytes, mononuclear cell trafficking to sites of endothelial inflammation, otherwise known as integrin alpha 4 chain/VLA-4, thymocytes, which acts as a receptor for fibronectin and CD106 (VCAM-1), /i>, /i>, CD49d This item specifically recognises rat CD49d, i>, i>, in vitro<, in vivo<
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunoprecipitation (IP), Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD49d
Short nameMOUSE Anti-RAT CD49d Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-RAT CD49d (Antibody to)
Alternative techniqueantibodies
Identity 6140
Gene ITGA4
Long gene name integrin subunit alpha 4
Synonyms gene CD49D
Synonyms gene name alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) , integrin
Synonyms CD49d
Synonyms name antigen CD49D alpha 4 subunit of VLA-4 receptor
Locus 2q31, 3
Discovery year 1991-08-06
Entrez gene record 3676
Pubmed identfication 1537388
Classification Integrin alpha subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000154212

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