Name : MOUSE Anti-RAT CD71:FITC Antibody
Supplier : MBS MONO
Price :431
SKU : GEN5208389621
| Also known as | CD71 |
| Other names | N/A, TR, Transferrin receptor protein 1, tfR, tfR1, transferrin receptor, transferrin receptor protein 1, Transferrin receptor protein 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD71 |
| Gene name synonims | N/A |
| Other gene names | TR, TfR, TfR1, Tfrc, Trfr, Trfr, Trfr, Tfrc |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2a |
| Clone | OX-26 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus) |
| Specificity and cross-reactivity | Alzheimer's, An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Clone MRC OX-26 also binds to a number of non-dividing normal tissues, Clone MRC OX-26 is reported as suitable for use in Electron Microscopy, Huntington's and Multiple Sclerosis, Parkinson's, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The balance between a sufficient amount of iron uptake and prevention of accumulation of excess iron within a cell, This particular antibody might cross react with speacies outside of the listed ones, Transferrin receptor (CD71), a homodimeric type II transmembrane protein, also known as transferrin receptor, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain, is vitally important to maintain cellular functions such as oxygen and electron transport and mitochondrial energy metabolism, thereby maintaining iron homeostasis, transferrin and ferritin have been identified as specialised proteins which control the uptake, transport and storage of free iron in tissues, whilst preventing permanent cell and tissue damage, CD71 This item recognises rat CD71 |
| Purification method | N/A |
| Form/Appearance | FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation | Anti-FITC Antibody |
| Gene target | CD71: |
| Short name | MOUSE Anti-RAT CD71:FITC Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label | FITC |
| Alternative name | MOUSE antibody to-RAT CD71:fluorecein (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11763 |
| Gene | TFRC |
| Long gene name | transferrin receptor |
| Synonyms gene name | CD71) , transferrin receptor (p90 |
| Synonyms | CD71 TFR1 p90 |
| Locus | 3q29 |
| Discovery year | 2001-06-22 |
| GenBank acession | X01060 |
| Entrez gene record | 7037 |
| Classification | CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000155714 |