Filters

MOUSE Anti-RAT CD80:FITC Antibody

MOUSE Anti-RAT CD80:FITC Antibody size: 100ug 398

Supplier MBS MONO
Price 398
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD80
Other names CD80, N/A, N/A, N/A, CD80
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD80
Gene name synonimsN/A
Other gene names Cd80, N/A, N/A, N/A
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone3H5
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus)
Specificity and cross-reactivity In contrast, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D_CD80 is a B cell activation antigen, _x000D_Clone 3H5 has been shown to block the co-stimulatory activity of rat CD80, a type I transmembrane glycoprotein and member of the Ig superfamily, and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, otherwise known as B7-1, the interaction of CD80 with CD152 has an inhibitory effect on T cell responses, which acts as a ligand for both CD28 and CD152 (CTLA-4), which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation and proliferation, CD80 This item specifically recognises rat CD80
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD80:
Short nameMOUSE Anti-RAT CD80:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative nameMOUSE antibody to-RAT CD80 molecule:fluorecein (Antibody to)
Alternative techniqueantibodies
Alternative to gene target B7 and B7-1 and B7, BT, CD80 and IDBG-51287 and ENSG00000121594 and 941, Cd80 and IDBG-160288 and ENSMUSG00000075122 and 12519, Cell surfaces, DNA-templated and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process, coreceptor activity, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045425 and positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process and biological process this GO :0045627 and positive regulation of T-helper 1 cell differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0015026: coreceptor activity, this GO :0015026: coreceptor activity, 1 and BB1 and CD28LG and CD28LG1 and LAB7, 27986 and IDBG-632750 and ENSBTAG00000018059 and 407131, CD80 molecule
Identity 1700
Gene CD80
Long gene name CD80 molecule
Synonyms gene CD28LG CD28LG1
Synonyms gene name B7-1 antigen) CD80 molecule , CD80 antigen (CD28 antigen ligand 1
Synonyms B7, 1 B7-1
Synonyms name B-lymphocyte activation antigen B7
Locus 3q13, 33
Discovery year 1993-12-14
Entrez gene record 941
Pubmed identfication 1370389
RefSeq identity NM_005191
Classification C2-set domain containing CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000159419

Similar products

Subscribe to our Newsletter